Osteopathic Manipulative Treatment for Immune Boosting in Healthy Adults
Trial Summary
Will I have to stop taking my current medications?
The trial requires that you must not be using or have recently used any immune-altering medications like corticosteroids, cyclosporin, tacrolimus, and pimecrolimus. If you are on these medications, you would need to stop taking them to participate.
What data supports the effectiveness of the treatment Osteopathic Manipulative Treatment (OMT) for immune boosting in healthy adults?
Is osteopathic manipulative treatment (OMT) generally safe for humans?
How is osteopathic manipulative treatment (OMT) unique for boosting the immune system?
Osteopathic manipulative treatment (OMT) is unique because it is a hands-on, noninvasive therapy that may enhance immune function by improving lymphatic movement, which is different from conventional drug-based approaches. This treatment is based on the principles of osteopathic medicine, focusing on the body's natural ability to heal itself.128910
What is the purpose of this trial?
The goal of this clinical trial is to determine whether osteopathic manipulative treatment (OMT) enhances immune system readiness in healthy adults compared to exercise or sham light treatment. Specifically, the goal of this study is to assess circulating immune cells and signaling molecules in the blood in response to these various treatments.It aims to compare: Complete Blood Counts (CBC) and blood immune signaling molecule levels in healthy adults in response to OMT, sham light touch, and exercise, with measurements taken at multiple time points.Researchers will compare immune blood cells and signaling molecules in response to OMT versus sham light touch and exercise within the same group of healthy adults measured at three time points for each of the three total visits.Participants will do a 15-minute OMT session, a 15-minute light sham session, or a 15-minute exercise session at each of their three separate visits (they will do one of each over the course of their 3 appointments in random order). They will have three blood draws taken at each of those three visits. They will also fill out a Global Physical Activity Questionnaire (GPAQ) survey to assess their level of physical activity throughout the study.
Research Team
Brian Loveless, DO
Principal Investigator
Professor of NMM/OMM and Chief Medical Officer of WesternU Health
Eligibility Criteria
This trial is for healthy adults interested in how different treatments might affect their immune system. Participants will be involved in three separate sessions, each including a unique treatment: osteopathic manipulative treatment (OMT), sham light touch, or exercise. They must complete a physical activity survey and agree to blood draws during visits.Inclusion Criteria
Exclusion Criteria
Timeline
Screening
Participants are screened for eligibility to participate in the trial
Treatment
Participants undergo three different interventions: OMT, sham light touch, and exercise, each followed by a 3-week washout period
Follow-up
Participants are monitored for safety and effectiveness after treatment
Treatment Details
Interventions
- Osteopathic Manipulative Treatment (OMT)
Osteopathic Manipulative Treatment (OMT) is already approved in United States, European Union for the following indications:
- Carpal Tunnel Syndrome
- Carpal Tunnel Syndrome
Find a Clinic Near You
Who Is Running the Clinical Trial?
Western University of Health Sciences
Lead Sponsor
American Osteopathic Foundation
Collaborator