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MOS Prebiotic for Gut Health in Healthy Older Adults

Research Sponsored by University of Florida
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Adults 50-99 years of age
Be older than 18 years old
Screening 3 weeks
Treatment Varies
Follow Up 14 days
Awards & highlights

Study Summary

This trial studies how baker's yeast-derived sugars can improve gut health and gut bacteria in older adults.

Who is the study for?
This trial is for healthy older adults aged 60-99 who can consent in English and are willing to follow the study procedures. It's not suitable for those with kidney disease, gastrointestinal surgeries or conditions, yeast allergies, current cancer treatment, recent antibiotic use, or if they're taking certain medications like laxatives.Check my eligibility
What is being tested?
The study is testing whether a yeast extract called Mannooligosaccharides (MOS) has prebiotic benefits that could improve gut function and alter fecal microbiota in older adults.See study design
What are the potential side effects?
Potential side effects may include changes in digestive functions such as bloating, gas, constipation or diarrhea due to the prebiotic nature of MOS affecting gut bacteria.

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below
I am between 50 and 99 years old.


Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~14 days
This trial's timeline: 3 weeks for screening, Varies for treatment, and 14 days for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Mean daily rating of gastrointestinal symptoms

Trial Design

1Treatment groups
Experimental Treatment
Group I: MannooligosaccharidesExperimental Treatment1 Intervention
Mannooligosaccharides yeast extract

Find a Location

Who is running the clinical trial?

University of FloridaLead Sponsor
1,340 Previous Clinical Trials
715,685 Total Patients Enrolled
Lallemand Bio-IngredientsOTHER
3 Previous Clinical Trials
68 Total Patients Enrolled

Media Library

Healthy Subjects Research Study Groups: Mannooligosaccharides
Healthy Subjects Clinical Trial 2023: Mannooligosaccharides Highlights & Side Effects. Trial Name: NCT05939336 — N/A
Mannooligosaccharides 2023 Treatment Timeline for Medical Study. Trial Name: NCT05939336 — N/A

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Does this clinical trial encompass elderly individuals over 75 years of age?

"This clinical trial is recruiting participants who are between 60 and 99 years of age."

Answered by AI

Which individuals meet the eligibility criteria for this clinical trial?

"Qualified applicants should be between 60 and 99 years old, with no pre-existing conditions. This clinical trial has a total of 20 spots available for enrollment."

Answered by AI

Are there still opportunities for individuals to participate in this research?

"Per data hosted on clinicaltrials.gov, this particular medical study is not actively seeking participants at present. It was first posted to the website in August of 2023 and last updated in July of 2023. Nevertheless, there are still 797 other trials that are currently accepting patients for participation."

Answered by AI

Who else is applying?

What site did they apply to?
Food Science and Human Nutrition Department, University of Florida
What portion of applicants met pre-screening criteria?
Met criteria
~12 spots leftby Apr 2025