MOS Prebiotic for Gut Health in Healthy Older Adults
Trial Summary
Will I have to stop taking my current medications?
The trial requires that you stop using antibiotics, laxatives, and antidiarrheal medications before participating. If you are using any of these, you will need to stop them to be eligible for the study.
What data supports the effectiveness of the treatment Mannooligosaccharides for gut health in healthy older adults?
Is Mannooligosaccharides (MOS) safe for human consumption?
How does the MOS prebiotic treatment for gut health in healthy older adults differ from other treatments?
The MOS prebiotic treatment is unique because it specifically targets gut health by enhancing the diversity of beneficial gut bacteria, which is particularly important for older adults. Unlike other treatments, MOS focuses on modulating the gut microbiota composition, potentially improving overall gut health and resilience in this age group.110111213
What is the purpose of this trial?
Mannooligosaccharides (MOS) derived from baker's yeast may have prebiotic properties such as improving gastrointestinal function. The aims of this study are to determine the effect of MOS on gastrointestinal function and symptoms and fecal microbiota in older adults.
Eligibility Criteria
This trial is for healthy older adults aged 60-99 who can consent in English and are willing to follow the study procedures. It's not suitable for those with kidney disease, gastrointestinal surgeries or conditions, yeast allergies, current cancer treatment, recent antibiotic use, or if they're taking certain medications like laxatives.Inclusion Criteria
Exclusion Criteria
Timeline
Screening
Participants are screened for eligibility to participate in the trial
Treatment
Participants receive 15 g per day of yeast-derived mannooligosaccharides to evaluate effects on gastrointestinal symptoms, stool frequency, fecal microbiome, and urinary metabolites
Follow-up
Participants are monitored for safety and effectiveness after treatment
Treatment Details
Interventions
- Mannooligosaccharides
Find a Clinic Near You
Who Is Running the Clinical Trial?
University of Florida
Lead Sponsor
Lallemand Bio-Ingredients
Collaborator