20 Participants Needed

Ketone Supplement for Colorectal Cancer Prevention

(BHB-CRC Trial)

BW
Overseen ByBryson W Katona, MD, PhD
Age: 18+
Sex: Any
Trial Phase: Academic
Sponsor: Abramson Cancer Center of the University of Pennsylvania
No Placebo GroupAll trial participants will receive the active study treatment (no placebo)

What You Need to Know Before You Apply

What is the purpose of this trial?

This trial is testing a BHB supplement, which is a type of ketone used for energy, in patients having a colonoscopy or flexible sigmoidoscopy. The goal is to see if the supplement is safe and if it changes the cells in the colon.

Who Is on the Research Team?

BW

Bryson W Katona, MD, PhD

Principal Investigator

University of Pennsylvania

Are You a Good Fit for This Trial?

This trial is for adults over 18 who can consent and are scheduled for a standard colonoscopy or flexible sigmoidoscopy. It's not suitable for those with diabetes on medication, severe kidney disease, active cancer treatment, pregnancy, incarceration, under 18s, history of bowel diseases or recent fasting diets.

Inclusion Criteria

Can provide informed consent
I am scheduled for a colonoscopy or sigmoidoscopy as part of my routine care.

Exclusion Criteria

I have a history of inflammatory bowel disease.
I have diabetes and am currently receiving treatment for it.
I am currently undergoing treatment for my cancer.
See 4 more

Timeline for a Trial Participant

Screening

Participants are screened for eligibility to participate in the trial

2-4 weeks

Treatment

Participants receive BHB supplementation through oral administration of HVMN Ketone-IQ for 4 weeks

4 weeks
Weekly monitoring visits

Follow-up

Participants are monitored for safety and effectiveness after treatment

Approximately 2 years

What Are the Treatments Tested in This Trial?

Interventions

  • R-1,3-Butanediol
Trial Overview The study tests if taking β-hydroxybutyrate (BHB) supplement is feasible for people getting routine colon checks. BHB is thought to help in preventing colorectal cancer.
How Is the Trial Designed?
1Treatment groups
Experimental Treatment
Group I: BHB supplementationExperimental Treatment1 Intervention

Find a Clinic Near You

Who Is Running the Clinical Trial?

Abramson Cancer Center of the University of Pennsylvania

Lead Sponsor

Trials
360
Recruited
108,000+

Abramson Cancer Center at Penn Medicine

Lead Sponsor

Trials
425
Recruited
464,000+
Unbiased ResultsWe believe in providing patients with all the options.
Your Data Stays Your DataWe only share your information with the clinical trials you're trying to access.
Verified Trials OnlyAll of our trials are run by licensed doctors, researchers, and healthcare companies.
Back to top
Terms of Service·Privacy Policy·Cookies·Security