Repeat Surgical Management of Recurrent GBM for Glioblastoma
Phase-Based Progress Estimates
Effectiveness
Safety
Glioblastoma+3 More
Repeat Surgical Management of Recurrent GBM - ProcedureEligibility
18+
All Sexes
What conditions do you have?
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Eligibility
18+
All Sexes
What conditions do you have?
Select
Study Summary
This trial is important because it will help neurosurgeons manage patients with recurrent GBM in the best way possible.
Eligible Conditions
- Glioblastoma
Treatment Effectiveness
Effectiveness Progress
Study Objectives
1 Primary · 5 Secondary · Reporting Duration: Follow-up for 5 Years or until death
Year 5
Discharge to a location other than home
Aphasia
Incidence of peri-operative non-neurological complications (wound infection, CSF leaks)
Length of Overall Survival
Total length of hospitalization / palliative care / nursing home
Total number of days spent outside a hospital or nursing care facility.
Trial Safety
Safety Progress
Trial Design
2 Treatment Groups
Management Without Re-operation
1 of 2
Repeat Surgical Resection
1 of 2
Active Control
Experimental Treatment
250 Total Participants · 2 Treatment Groups
Primary Treatment: Repeat Surgical Management of Recurrent GBM · No Placebo Group · N/A
Repeat Surgical Resection
Procedure
Experimental Group · 1 Intervention: Repeat Surgical Management of Recurrent GBM · Intervention Types: ProcedureManagement Without Re-operation
Procedure
ActiveComparator Group · 1 Intervention: Repeat Surgical Management of Recurrent GBM · Intervention Types: ProcedureTrial Logistics
Trial Timeline
Approximate Timeline
Screening: ~3 weeks
Treatment: Varies
Reporting: follow-up for 5 years or until death
Who is running the clinical trial?
University of AlbertaLead Sponsor
805 Previous Clinical Trials
369,383 Total Patients Enrolled
1 Trials studying Glioblastoma
40 Patients Enrolled for Glioblastoma
Eligibility Criteria
Age 18+ · All Participants · 4 Total Inclusion Criteria
Mark “yes” if the following statements are true for you:rates
The attending surgeon thinks that re-operation may improve the quality of survival rates.
You have previously histologically confirmed and surgically resected Glioblastoma.
Craniotomy is a surgery that is used to remove a tumor from the brain
About The Reviewer
Michael Gill holds a Bachelors of Science in Integrated Science and Mathematics from McMaster University. During his degree he devoted considerable time modeling the pharmacodynamics of promising drug candidates. Since then, he has leveraged this knowledge of the investigational new drug ecosystem to help his father navigate clinical trials for multiple myeloma, an experience which prompted him to co-found Power Life Sciences: a company that helps patients access randomized controlled trials.
References
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- Chen, Min Wei, Ahmed A. Morsy, Sai Liang, and Wai Hoe Ng. 2016. “Re-do Craniotomy for Recurrent Grade IV Glioblastomas: Impact and Outcomes from the National Neuroscience Institute Singapore”. World Neurosurgery. Elsevier BV. doi:10.1016/j.wneu.2015.10.051.
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