Repeat Surgical Management of Recurrent GBM for Glioblastoma

Phase-Based Progress Estimates
1
Effectiveness
1
Safety
Glioblastoma+3 More
Repeat Surgical Management of Recurrent GBM - Procedure
Eligibility
18+
All Sexes
What conditions do you have?
Select

Study Summary

This trial is important because it will help neurosurgeons manage patients with recurrent GBM in the best way possible.

Eligible Conditions
  • Glioblastoma

Treatment Effectiveness

Effectiveness Progress

1 of 3

Other trials for Glioblastoma

Study Objectives

1 Primary · 5 Secondary · Reporting Duration: Follow-up for 5 Years or until death

Year 5
Discharge to a location other than home
Aphasia
Incidence of peri-operative non-neurological complications (wound infection, CSF leaks)
Length of Overall Survival
Total length of hospitalization / palliative care / nursing home
Total number of days spent outside a hospital or nursing care facility.

Trial Safety

Safety Progress

1 of 3

Other trials for Glioblastoma

Trial Design

2 Treatment Groups

Management Without Re-operation
1 of 2
Repeat Surgical Resection
1 of 2
Active Control
Experimental Treatment

250 Total Participants · 2 Treatment Groups

Primary Treatment: Repeat Surgical Management of Recurrent GBM · No Placebo Group · N/A

Repeat Surgical Resection
Procedure
Experimental Group · 1 Intervention: Repeat Surgical Management of Recurrent GBM · Intervention Types: Procedure
Management Without Re-operation
Procedure
ActiveComparator Group · 1 Intervention: Repeat Surgical Management of Recurrent GBM · Intervention Types: Procedure

Trial Logistics

Trial Timeline

Approximate Timeline
Screening: ~3 weeks
Treatment: Varies
Reporting: follow-up for 5 years or until death

Who is running the clinical trial?

University of AlbertaLead Sponsor
805 Previous Clinical Trials
369,383 Total Patients Enrolled
1 Trials studying Glioblastoma
40 Patients Enrolled for Glioblastoma

Eligibility Criteria

Age 18+ · All Participants · 4 Total Inclusion Criteria

Mark “yes” if the following statements are true for you:
rates The attending surgeon thinks that re-operation may improve the quality of survival rates.
You have previously histologically confirmed and surgically resected Glioblastoma.
Craniotomy is a surgery that is used to remove a tumor from the brain

About The Reviewer

Michael Gill preview

Michael Gill - B. Sc.

First Published: October 1st, 2021

Last Reviewed: October 1st, 2022

Michael Gill holds a Bachelors of Science in Integrated Science and Mathematics from McMaster University. During his degree he devoted considerable time modeling the pharmacodynamics of promising drug candidates. Since then, he has leveraged this knowledge of the investigational new drug ecosystem to help his father navigate clinical trials for multiple myeloma, an experience which prompted him to co-found Power Life Sciences: a company that helps patients access randomized controlled trials.

References