24 Participants Needed

Sprint Interval Training for Endurance Performance

JG
Overseen ByJenna Gillen Assistant Professor, PhD
No Placebo GroupAll trial participants will receive the active study treatment (no placebo)

What You Need to Know Before You Apply

What is the purpose of this trial?

This trial explores how short bursts of sprint interval training can improve endurance and muscle adaptations in women. Researchers aim to determine if training during different phases of the menstrual cycle affects these improvements. Specifically, they compare the follicular phase (days 1-14) and the luteal phase (days 15-28) of the menstrual cycle. The trial seeks healthy women who regularly exercise, maintain a stable weight, and have regular, predictable menstrual cycles. As an unphased trial, it offers participants the opportunity to contribute to new insights on optimizing fitness routines for women.

Will I have to stop taking my current medications?

Yes, you will need to stop taking medications that affect blood glucose, lipid metabolism, or substrate metabolism, such as corticosteroids or NSAIDs, to participate in this trial.

What prior data suggests that sprint interval training is safe for improving endurance performance in women?

Research shows that sprint interval training (SIT) is generally manageable for most people. No specific evidence indicates that performing this training at different times in the menstrual cycle is unsafe. Studies examining the luteal phase, a part of the menstrual cycle, have shown that this training can lead to unique muscle changes without major negative effects.

Previous research found that aligning high-frequency SIT with menstrual cycle phases can influence muscle changes and overall body response. However, these studies did not report serious safety issues. Some studies noted mood changes, such as increased anxiety or tension during the luteal phase, but these were not directly linked to the exercise.

Since this trial focuses on exercise rather than a new drug or treatment, the risk of negative effects is usually lower. Overall, sprint interval training is considered safe for healthy individuals, though experiences can vary. Always consult a healthcare provider before starting any new exercise program.12345

Why are researchers excited about this trial?

Researchers are excited about the Sprint Interval Training because it explores how timing exercise with different phases of the menstrual cycle might enhance endurance performance. Unlike traditional training programs that don't consider menstrual cycle phases, this approach tailors exercise timing to the follicular (days 1-14) or luteal (days 15-28) phases. This individualized strategy could optimize hormonal influences on performance, potentially leading to more effective results for female athletes. By aligning training with hormonal fluctuations, this method might unlock new insights into maximizing athletic performance.

What evidence suggests that this trial's treatments could be effective for improving endurance performance?

Research shows that sprint interval training (SIT) can improve endurance and lead to positive changes in muscles. This trial will compare SIT conducted during different phases of the menstrual cycle. Participants in the "Follicular Phase Training" arm will engage in SIT during the follicular phase (approximately days 1-14), while those in the "Luteal Phase Training" arm will train during the luteal phase (approximately days 15-28). Studies have found that doing SIT at different times in the menstrual cycle can cause different muscle changes in women. Some research suggests that training during the luteal phase might affect performance results. It remains unclear if these changes differ significantly from those in the follicular phase. Overall, SIT is a promising way to enhance endurance by increasing muscle capacity.23678

Are You a Good Fit for This Trial?

This trial is for healthy, active women with a consistent menstrual cycle of 27-35 days and minimal variability. They should be non-smokers, engage in regular exercise (2-4 times per week), have a BMI of 18-27 kg/m2, and show evidence of ovulation. Women who don't meet these physical activity levels or menstrual cycle criteria cannot participate.

Inclusion Criteria

VO2peak of 'good' or above based on American College of Sport Medicine (ACSM) normative values (greater than 35.0ml/kg/min)
Weight stable (within ± 2kg for at least 6 months)
Non-smoker
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Exclusion Criteria

Pregnant or post-partum in the last 12 months, lactating or breast feeding within 3 months of the start of study, or menopausal
I have been diagnosed with a heart or metabolic disease, or have abnormal hormone levels or PCOS.
I am currently using or have used oral contraceptives in the last 3 months.
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Timeline for a Trial Participant

Screening

Participants are screened for eligibility to participate in the trial

2-4 weeks

Treatment

Participants perform 6 sessions of sprint interval training over 2 weeks in either the Follicular Phase or Luteal Phase of their menstrual cycle

2 weeks
6 visits (in-person)

Follow-up

Participants are monitored for safety and effectiveness after treatment

4 weeks

What Are the Treatments Tested in This Trial?

Interventions

  • Sprint Interval Training
Trial Overview The study is testing how sprint interval training affects endurance and muscle metabolism in women during different phases of their menstrual cycle. It compares the effects when training is done in either the follicular or luteal phase over two weeks.
How Is the Trial Designed?
2Treatment groups
Experimental Treatment
Active Control
Group I: Luteal Phase TrainingExperimental Treatment1 Intervention
Group II: Follicular Phase TrainingActive Control1 Intervention

Find a Clinic Near You

Who Is Running the Clinical Trial?

University of Toronto

Lead Sponsor

Trials
739
Recruited
1,125,000+

Published Research Related to This Trial

A scoping review of 69 studies on high-intensity interval training (HIIT) in older adults found that HIIT protocols are generally well-tolerated and can provide significant health benefits, particularly in improving cardiorespiratory fitness.
Most research has focused on healthy older adults, highlighting a need for larger studies and more investigation into HIIT's effects on older adults with various health conditions.
High-Intensity Interval Training in Older Adults: a Scoping Review.Marriott, CFS., Petrella, AFM., Marriott, ECS., et al.[2021]

Citations

The Impact of Menstrual Cycle Phase on Athletes ...Figure 2 demonstrates that more performance outcomes were relatively reduced in the late luteal phase than any other MC phase. This indicates that pre-menstrual ...
Menstrual Cycle Phase-Based Interval Training Yields ...Our findings show that synching high-frequency SIT with menstrual cycle phases induces distinct muscle adaptations and affects phenotype in eumenorrheic female ...
Cycle Phases on Repeated Sprint AbilityThe aim of this study was to compare performance, physiological and perceptual differences when performing a repeated sprint ability (RSA) exercise.
Effects of menstrual cycle phases on athletic performance ...Fifty-eight percent reported significant phase effects on at least one performance-related outcome, although the direction and magnitude varied between studies.
Influence of Menstrual Cycle Phase on Adaptations to ...Sprint interval training improves endurance performance and induces metabolic adaptations in muscle. Most research demonstrating these ...
The Sprint-Interval Exercise Using a Spinning Bike Improves ...In the present study, in samples taken during the late luteal phase, prostaglandin and HsCRP levels were shown to be significantly higher in dysmenorrhea groups ...
The effect of menstrual cycle and exercise intensity on ...Women in the luteal phase displayed higher anxiety, tension, depression, hostility and lower arousal, affect and motivation pre-exercise.
Impact of Menstrual cycle-based Periodized training on ... - TrialsThis randomized, controlled trial will provide evidence of any differential effects of exercise periodization during different phases of the menstrual cycle in ...
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