Autologous Adipose-Derived SVF (Stromal Vascular Fraction) for Osteoarthritis

Phase-Based Progress Estimates
Mayo Clinic in Rochester, Rochester, MNOsteoarthritis+1 MoreAutologous Adipose-Derived SVF (Stromal Vascular Fraction) - Biological
40 - 70
All Sexes
What conditions do you have?

Study Summary

This trial is testing whether it is safe and feasible to inject a person's own fat-derived cells into their knee to treat osteoarthritis.

Eligible Conditions
  • Osteoarthritis of the Knee

Treatment Effectiveness

Study Objectives

1 Primary · 0 Secondary · Reporting Duration: 2 years

2 years
Adverse Events

Trial Safety

Trial Design

2 Treatment Groups

SVF (Stromal Vascular Fraction) Group
1 of 2
Placebo Group
1 of 2

Experimental Treatment

Non-Treatment Group

30 Total Participants · 2 Treatment Groups

Primary Treatment: Autologous Adipose-Derived SVF (Stromal Vascular Fraction) · Has Placebo Group · Phase 1

SVF (Stromal Vascular Fraction) Group
Experimental Group · 1 Intervention: Autologous Adipose-Derived SVF (Stromal Vascular Fraction) · Intervention Types: Biological
Placebo Group
PlaceboComparator Group · 1 Intervention: Placebo · Intervention Types: Drug

Trial Logistics

Trial Timeline

Screening: ~3 weeks
Treatment: Varies
Reporting: 2 years

Who is running the clinical trial?

Mayo ClinicLead Sponsor
2,960 Previous Clinical Trials
3,449,456 Total Patients Enrolled
27 Trials studying Osteoarthritis
2,790 Patients Enrolled for Osteoarthritis
Shane A ShapiroPrincipal InvestigatorMayo Clinic
1 Previous Clinical Trials
1 Trials studying Osteoarthritis

Eligibility Criteria

Age 40 - 70 · All Participants · 11 Total Inclusion Criteria

Mark “Yes” if the following statements are true for you:
You must be between the ages of 40 and 70, regardless of your gender.
You have tried conservative treatments like physical therapy, medication, or injections for at least 3 months before.
Your knee is not experiencing any major issues or pain.

Frequently Asked Questions

Does this experimental procedure require subjects to be of a particular age?

"This research is open to those aged 40 or older but not exceeding the age of 70." - Anonymous Online Contributor

Unverified Answer

How many individuals have volunteered for this experiment?

"Affirmative. The clinical trial is actively in session, as per the information on; it was first introduced on July 1st 2019 and last updated on May 26th 2022. 30 participants will be accepted at 2 different locations for this medical study." - Anonymous Online Contributor

Unverified Answer

Are there any vacancies left for participants in this clinical experiment?

"Indeed, displays that this trial is currently seeking participants - it was posted on July 1st 2019 and last updated on May 26th 2022. Specifically, the study requires 30 subjects across 2 locations to be recruited." - Anonymous Online Contributor

Unverified Answer

To whom is this research open for participation?

"This clinical trial requires 30 participants, within the ages of 40 to 70 who suffer from arthrosis. Other prerequisites for enrolment include: Females with childbearing potential must take a pregnancy test and use adequate contraception (hormonal or barrier method or abstinence) between screening and 1 year after drug treatment ends; females with childbearing potential are defined as either premenopausal without sterilization surgery, or post-menopausal for less than 2 years; urine tests will be conducted prior to administering study drugs while serum tests can be done at a central lab; candidates should also have no issues walking unaided by any device such as walkers" - Anonymous Online Contributor

Unverified Answer

Could you elucidate the potential risks associated with Autologous Adipose-Derived SVF (Stromal Vascular Fraction) treatments?

"There is limited data backing Autologous Adipose-Derived SVF's safety and efficacy, thus it received a score of 1." - Anonymous Online Contributor

Unverified Answer
Please Note: These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.