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Other

Specific Substance for Smoking

N/A
Recruiting
Research Sponsored by Oregon Health and Science University
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Participants must be 21-40 years old
Be between 18 and 65 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up 1 year follow-up from baseline
Awards & highlights

Study Summary

This trial is looking at the reasons why some people who don't smoke every day still smoke, in order to help create better interventions to stop smoking.

Who is the study for?
This trial is for young adults aged 21-40 who smoke cigarettes or e-cigarettes occasionally (1-27 days in the past month) and sometimes binge drink. They must be fluent in English, right-handed, and not seeking substance use treatment. People with severe nicotine addiction, major illnesses, head trauma, CNS-affecting meds usage, current alcohol disorder, frequent marijuana use (>10 times last year), MRI issues like metal implants/pregnancy can't join.Check my eligibility
What is being tested?
The study is examining how a specific substance affects occasional smokers' behavior and brain function. Participants will either receive a placebo (a harmless inactive substance) or the study agent being tested to see its effects compared to no treatment at all.See study design
What are the potential side effects?
Since the side effects are not specified here for the 'study agent,' they could range from none to mild discomforts such as headaches or nausea depending on what's being tested. The placebo group should experience no side effects related to active ingredients.

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below
Select...
I am between 21 and 40 years old.

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~1 year follow-up from baseline
This trial's timeline: 3 weeks for screening, Varies for treatment, and 1 year follow-up from baseline for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Cigarette Craving and Associated Brain Activation
Impulsivity
Resting State Functional Connectivity
+1 more

Trial Design

2Treatment groups
Experimental Treatment
Placebo Group
Group I: Study AgentExperimental Treatment1 Intervention
Group II: PlaceboPlacebo Group1 Intervention

Find a Location

Who is running the clinical trial?

National Institute on Drug Abuse (NIDA)NIH
2,464 Previous Clinical Trials
2,618,533 Total Patients Enrolled
66 Trials studying Smoking
22,560 Patients Enrolled for Smoking
Oregon Health and Science UniversityLead Sponsor
973 Previous Clinical Trials
6,845,969 Total Patients Enrolled
4 Trials studying Smoking
3,746 Patients Enrolled for Smoking

Media Library

Study Agent (Other) Clinical Trial Eligibility Overview. Trial Name: NCT04281979 — N/A
Smoking Research Study Groups: Study Agent, Placebo
Smoking Clinical Trial 2023: Study Agent Highlights & Side Effects. Trial Name: NCT04281979 — N/A
Study Agent (Other) 2023 Treatment Timeline for Medical Study. Trial Name: NCT04281979 — N/A
Smoking Patient Testimony for trial: Trial Name: NCT04281979 — N/A

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Are individuals over the age of fifty eligible for enrollment in this research project?

"According to the eligibility requirements, those aged 21-25 may apply for this clinical trial. Additionally, there are 4 trials specifically intended for minors and 54 studies that focus on patients over 65 years of age."

Answered by AI

Does this research endeavor currently have open enrollment?

"This clinical trial is actively recruiting, as reflected on the listings found on clinicaltrials.gov. This study was first published in February 2020 and has recently been updated March 2021."

Answered by AI

To which demographic does this research opportunity apply?

"This research requires 60 individuals, aged between 21 and 25 years old, who have a history of smoking cigarettes in the past month. Additionally, participants must be right-handed and should report at least one instance of binge drinking as defined by NIAAA criteria (5 or more drinks per occasion for males, 4 or more drinks per occasion for females) within the last 90 days without any negative outcomes."

Answered by AI

How many individuals are eligible to participate in this experiment?

"Affirmative. The clinical trial data available on clinicaltrials.gov confirms that this medical study, which was initially published on February 25th 2020 is actively enrolling patients. 60 participants are needed from 1 site location."

Answered by AI

Who else is applying?

What state do they live in?
Oregon
What site did they apply to?
Oregon Health and Science University
What portion of applicants met pre-screening criteria?
Met criteria
Did not meet criteria
How many prior treatments have patients received?
0

Why did patients apply to this trial?

Beacuse id like to stop smoking snd i figured the only way i could do it was with some incentive.
PatientReceived 2+ prior treatments
I recently was diagnosed with heart failure and pulmonary hypertension. I can feel cigarettes killing me everyday and I want to quit.
PatientReceived 2+ prior treatments
Recent research and studies
clinicaltrials.govStudy
Effects of a Specific Substance in Smokers
Angelica Morales 2020. "Effects of a Specific Substance in Smokers". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT04281979.
~12 spots leftby Apr 2025
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