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Behavioural Intervention

Active rTMS for Smoking

N/A

Recruiting

Led By Mariya V Cherkasova, PhD

Research Sponsored by West Virginia University

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Be between 18 and 65 years old

Timeline

Screening 3 weeks

Treatment Varies

Follow Up within 1 hour following the delivery of rtms

Awards & highlights

Study Summary

This trial is testing different ways of thinking during a treatment called repetitive Transcranial Magnetic Stimulation (rTMS) to see if it can reduce cravings for smoking and change brain activity. The trial

Who is the study for?

This trial is for individuals who smoke at least 8 cigarettes daily, have no plans to quit in the next 3 months, and can safely undergo rTMS and fMRI. It's not specified who cannot participate, but typically those with metal implants or certain medical conditions may be excluded.Check my eligibility

What is being tested?

The study tests how different thinking strategies during rTMS affect smoking cravings and brain activity. Participants will try 'upregulation' (focusing on positive smoking experiences) and 'downregulation' (considering negative consequences) while viewing related images during sessions.See study design

What are the potential side effects?

rTMS may cause discomfort at the stimulation site, headache, lightheadedness, or seizures in rare cases. The side effects of fMRI are minimal but can include discomfort from lying still.

Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ within 1 hour following the delivery of rtms

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~within 1 hour following the delivery of rtms

This trial's timeline: 3 weeks for screening, Varies for treatment, and within 1 hour following the delivery of rtms for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.

Primary outcome measures

Change in neural activation during regulation of craving

Change in self-reported smoking cravings

Secondary outcome measures

Change in delay discounting performance for cigarettes

Change in neural activation during delay discounting performance for cigarettes

Other outcome measures

Resting-state brain activity

Trial Design

1Treatment groups

Experimental Treatment

Group I: Active rTMSExperimental Treatment1 Intervention

There is a single arm in this open-label pilot study. All participants will receive active rTMS paired with different types of behavioral priming (upregulation of craving, downregulation of craving, no regulation of craving).

Treatment

First Studied

Drug Approval Stage

How many patients have taken this drug

Repetitive transcranial magnetic stimulation (rTMS)

2017

Completed Phase 4

~700

Do I qualify?Apply below to find out

Find a Location

Who is running the clinical trial?

West Virginia UniversityLead Sponsor

176 Previous Clinical Trials

60,194 Total Patients Enrolled

Mariya V Cherkasova, PhDPrincipal InvestigatorWest Virginia University

1 Previous Clinical Trials

20 Total Patients Enrolled

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Is the enrollment for this medical study currently open?

"According to the information available on clinicaltrials.gov, this study is not currently open for enrollment. It was initially posted on February 1st, 2024 and last edited on January 19th, 2024. However, there are presently 30 other ongoing clinical trials actively seeking eligible participants."

Answered by AI

Do I meet the necessary criteria to participate in this research trial?

"To be eligible for participation in this clinical trial, individuals must demonstrate a commitment to quit smoking and fall within the age range of 18 to 60 years old. The study has capacity for approximately 20 qualified candidates."

Answered by AI

Is the recruitment for this research study limited to individuals who have reached or exceeded 18 years of age?

"Applicants who meet the criteria for this trial must be within the age range of 18 to 60. There are three separate trials specifically designed for individuals under 18 years old and twenty-two trials tailored for patients over the age of 65."

Answered by AI

Recent research and studies

clinicaltrials.govStudy

rTMS-concurrent Behavioral Priming for Reducing Smoking Cravings

Mariya V. Cherkasova 2024. "rTMS-concurrent Behavioral Priming for Reducing Smoking Cravings". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT06228235.

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