Nitrate-Enriched Beetroot Juice for Healthy Aging
(BOOST-X Trial)
What You Need to Know Before You Apply
What is the purpose of this trial?
This trial aims to determine if nitrate-enriched beetroot juice can enhance the benefits of exercise in older adults. Researchers pair this juice with a combination of endurance and resistance training to improve physical and mental function as people age. The trial compares the effects of the nitrate-rich juice to a placebo (inactive version) to assess any differences. Ideal participants are those over 60 who haven't engaged in regular exercise and are free from major chronic illnesses. As an unphased trial, this study provides a unique opportunity to contribute to understanding how natural supplements can enhance exercise benefits in aging populations.
Do I need to stop taking my current medications for the trial?
Yes, you may need to stop certain medications. The trial excludes participants using nitrate medications, high-dose statins, chronic corticosteroids, testosterone, or other anabolic hormones. If you're on these, you might need to stop them to join the trial.
Is there any evidence suggesting that nitrate-enriched beetroot juice is safe for humans?
Research has shown that beetroot juice with added nitrates is generally safe to drink. One study found that this juice lowered average blood pressure, potentially benefiting heart health. Another study suggested that athletes often use the juice to enhance performance due to its natural nitrates.
Each serving of the juice provides 400 mg of natural nitrates, a typical amount for improving stamina and endurance. Reports of negative effects from this amount are rare. However, as with any supplement, individual reactions may vary. Overall, the juice is considered well-tolerated, especially since it comes from natural sources like beets.12345Why are researchers excited about this trial?
Nitrate-enriched beetroot juice is unique because it harnesses the power of natural nitrates to potentially promote healthy aging. Unlike traditional treatments that often rely on pharmaceuticals, this approach uses a natural ingredient found in beetroot to improve blood flow and support cardiovascular health. Researchers are excited because nitrates in beetroot juice may enhance exercise efficiency and lower blood pressure, offering a simple, dietary-based intervention for aging-related concerns. This natural approach could provide a more accessible and less invasive alternative to existing medications.
What evidence suggests that nitrate-enriched beetroot juice might be an effective treatment for healthy aging?
Research shows that beetroot juice, rich in nitrates, can improve endurance and oxygen efficiency. Studies have found that it reduces tiredness, increases stamina, and boosts muscle strength. In one study, participants who drank beetroot juice exercised 16% longer. It also improves blood flow and muscle function, enhancing exercise performance. This trial will compare the effects of nitrate-enriched beetroot juice with a placebo to evaluate its potential for supporting healthy aging by enhancing exercise benefits.16789
Are You a Good Fit for This Trial?
This trial is for men and women aged 60 or older who are generally healthy, have not done regular exercise in the past year, and can give informed consent. People with chronic diseases that could affect participation or results cannot join.Inclusion Criteria
Timeline for a Trial Participant
Screening
Participants are screened for eligibility to participate in the trial
Treatment
Participants receive a nitrate-enriched dietary supplement combined with endurance and resistance training
Follow-up
Participants are monitored for safety and effectiveness after treatment
What Are the Treatments Tested in This Trial?
Interventions
- Nitrate enriched beetroot juice
Trial Overview
The study tests whether drinking nitrate-enriched beetroot juice along with a 12-week combined endurance and resistance exercise program improves health benefits from exercise in older adults, compared to nitrate-depleted beetroot juice.
How Is the Trial Designed?
2
Treatment groups
Experimental Treatment
Placebo Group
Participants will be randomized to an intervention in which they take 800 mg (2 x 400 mg) nitrate-enriched beetroot juice drink \[Beet It Sport Nitrate 400 (70 ml per drink)\]. Both nitrate and placebo will be purchased from Beet It.
Participants will be randomized to an intervention in which they take 800 mg (2 x 400 mg) nitrate-deprived, manufacturer-matched beetroot juice drink \[Beet It Sport Nitrate 400 (70 ml per drink)\]. Both nitrate and placebo will be purchased from Beet It.
Find a Clinic Near You
Who Is Running the Clinical Trial?
Florida Institute for Human and Machine Cognition
Lead Sponsor
Citations
Beetroot Juice Supplementation as a Healthy Aging Strategy ...
Background: Findings show that beetroot-derived nitrates can improve endurance, oxygen efficiency, muscular power, recovery and cardiovascular ...
Effects of Beetroot Juice Supplementation on ... - PMC - NIH
The results show that supplementation with beetroot juice reduced VO2 to 80% VT1 and there was a statistical trend to improvement in higher intensity exercise ( ...
3.
beet-it.us
beet-it.us/pages/science?srsltid=AfmBOoogi5-Z4XYBIgUiKXLZKeGrUWDq2nbaovLUqyyKOWbh6QIrMv1iThe Science Behind Beet It – Nitrate Research & Benefits
Backed by 300+ research projects, Beet It Sport shows how natural dietary nitrate from beet juice reduces fatigue, increases stamina, and powers athletes.
Nitrate-Enriched Beetroot Juice for Healthy Aging (BOOST ...
The BOOST-X medical study, being run by Florida Institute for Human and Machine Cognition, needs participants to evaluate whether Nitrate enriched beetroot ...
Effects of increased nitrate intake from beetroot juice on ...
In the present study, the decrease in the oxLDL/NOx ratio after the increased nitrate intake apparently resulted mainly from the pronounced increases in plasma ...
6.
beet-it.us
beet-it.us/pages/frequently-asked-questions?srsltid=AfmBOoqIipLy407N0HUwW2GdzqbYpjpzCsg4usVYBM710tdKlcFGUDViFAQ - Beet It Sport US
Find answers to common questions about Beet It Sport natural nitrates, athletic performance, usage timing, and product safety. Fuel your game today!
Sports Research
Beet It Sport shots guarantee 400mg of natural nitrate from concentrated beetroot juice – the amount required for sports performance improvement.
8.
examine.com
examine.com/supplements/nitrate/?srsltid=AfmBOorfZVPJ1UyDG5O2n387Ky8XAYWlGJ9mDFIneIAQBQq1t17OYaJINitrate benefits, dosage, and side effects
Nitrate supplements are claimed to improve blood pressure, cardiovascular health, and exercise performance.
9.
nutraingredients.com
nutraingredients.com/Article/2020/12/24/Athletes-misled-by-beetroot-products-warns-shot-market-leader/Athletes misled by beetroot products, warns shot market ...
'Beet It Sport Nitrate 400' 70ml shots each contain 400mg of nitrates sourced from British and German beets and bottled in the UK where the ...
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