← Back to Search

General Anesthetic

Propofol for Migraine (Propofol2014 Trial)

N/A

Waitlist Available

Led By Deryk Walsh, MD

Research Sponsored by University of Texas Southwestern Medical Center

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Be younger than 65 years old

Timeline

Screening 3 weeks

Treatment Varies

Follow Up assessments of nprs pain scores on a scale of 0-10 with 0 being no pain and 10 being severe pain at 24 and 48 hours after discharge from infusion

Awards & highlights

Propofol2014 Trial Summary

This trial will study the use of low-dose propofol to treat migraines in children. The goal is to see if it is effective and safe, and to determine the best dose.

Eligible Conditions

Migraine

Propofol2014 Trial Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ assessments of nprs pain scores on a scale of 0-10 with 0 being no pain and 10 being severe pain at 24 and 48 hours after discharge from infusion

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~assessments of nprs pain scores on a scale of 0-10 with 0 being no pain and 10 being severe pain at 24 and 48 hours after discharge from infusion

This trial's timeline: 3 weeks for screening, Varies for treatment, and assessments of nprs pain scores on a scale of 0-10 with 0 being no pain and 10 being severe pain at 24 and 48 hours after discharge from infusion for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.

Primary outcome measures

Improvement in Headache Pain Score

Secondary outcome measures

NPRS Pain Scores at 24 and 48 Hours Post Infusion

Total Propofol Dose

Propofol2014 Trial Design

1Treatment groups

Experimental Treatment

Group I: Propofol infusionExperimental Treatment1 Intervention

All subjects will be treated with an intravenous propofol infusion at the following escalating rate schedule: 20 mcg/kg/min for 10 minutes, followed by an increase to 30 mcg/kg/min for 10 minutes and then by an increase to 40 mcg/kg/min for 40 minutes

Treatment

First Studied

Drug Approval Stage

How many patients have taken this drug

Propofol

2017

Completed Phase 4

~1530

Do I qualify?Apply below to find out

Find a Location

Who is running the clinical trial?

University of Texas Southwestern Medical CenterLead Sponsor

1,047 Previous Clinical Trials

1,053,759 Total Patients Enrolled

1 Trials studying Migraine

45 Patients Enrolled for Migraine

Deryk Walsh, MDPrincipal Investigator - Children's Medical Center Dallas

University of Texas Southwestern Medical Center

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Is there an upper age-limit for applicants to this experiment?

"To qualify for this trial, applicants need to be between 7 and 18 years old. Additionally, there are 55 clinical trials designed specifically for minors and 239 studies intended for the elderly population."

Answered by AI

What maladies is Propofol commonly administered to address?

"Propofol is a commonly used sedative for medical procedures, as well as monitored anesthesia care therapy, sedative therapy and other anesthetic operations."

Answered by AI

Is this trial currently accepting new participants?

"Confirmed. According to the information presented on clinicaltrials.gov, this medical trial was first posted in June 2015 and is currently seeking volunteers for participation. 40 individuals need to be enrolled at a single site."

Answered by AI

Is it feasible for me to participate in this experiment?

"Individuals aged between 7 and 18 years old with a diagnosis of migraine can register for this medical trial. 40 participants in total are being accepted by the research team."

Answered by AI

What is the cumulative amount of participants enrolled in this research project?

"Affirmative. Clinicaltrials.gov is displaying that this research initiative, which was published on June 1st 2015, is actively seeking participants. Approximately 40 volunteers must be identified at one medical centre."

Answered by AI

What other investigations have been conducted to assess the effects of Propofol?

"Currently, 12 Propofol studies are in Phase 3 with an additional 72 trials still being conducted. In particular, Jinan Shandong is the major hub of research for this medication while there also exist 251 other study locations worldwide."

Answered by AI

Recent research and studies

clinicaltrials.govStudy

Low- Dose Propofol Infusion as an Abortive Treatment for Migraine Headaches in Pediatric Patients

Deryk Walsh 2015. "Low- Dose Propofol Infusion as an Abortive Treatment for Migraine Headaches in Pediatric Patients". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT02485418.