Tendon Variation Study for Hand Anomalies

(LCV Trial)

Age: 18+
Sex: Any
Trial Phase: Academic
Sponsor: Russell Sage College
No Placebo GroupAll trial participants will receive the active study treatment (no placebo)

What You Need to Know Before You Apply

What is the purpose of this trial?

This trial examines the link between thumb arthritis and a specific tendon connection in the wrist, known as the Linburg-Comstock variation (LCV). Thumb arthritis can cause pain and make everyday tasks difficult. The study aims to determine if individuals with LCV are more likely to develop this type of arthritis. Participants undergo a simple physical exam to check for LCV if diagnosed with thumb arthritis. Those diagnosed with thumb arthritis and who have started non-surgical treatments may be suitable for this trial. As an unphased study, this trial offers a unique opportunity to contribute to understanding the potential connection between LCV and thumb arthritis.

Do I need to stop taking my current medications for this trial?

The trial information does not specify whether you need to stop taking your current medications. It's best to discuss this with the trial coordinators or your doctor.

What prior data suggests that this study's examination method is safe?

The study focuses on observing a specific tendon difference in the hand, known as the Linburg-Comstock variation (LCV), to understand its potential link to thumb arthritis. As this study involves only observation and no treatment, safety concerns do not arise. Participants will not receive any experimental drugs or procedures. Instead, simple physical exams will check for the tendon difference. This research solely aims to collect observational data to explore the connection between tendon differences and arthritis.

Why are researchers excited about this trial?

Researchers are excited about this trial because it aims to provide a better understanding of tendon variations in individuals with hand anomalies. Unlike traditional treatments that focus on managing symptoms or correcting anomalies through surgery or therapy, this study uses a descriptive method to identify specific tendon variations through clinical exams. This approach could lead to more personalized treatment plans by identifying unique anatomical differences that might influence surgical or therapeutic outcomes. By shedding light on these variations, the trial could pave the way for more targeted and effective interventions in the future, potentially improving recovery times and functional outcomes for patients.

What evidence suggests that this study's examination method could be effective for understanding CMC arthritis?

In this study, researchers are examining a condition called Linburg-Comstock variation (LCV), a connection between tendons in the hand. They aim to determine if a link exists between LCV and a type of thumb arthritis known as CMC arthritis. Currently, no clear evidence shows that LCV causes or affects CMC arthritis. However, the study seeks to discover if individuals with LCV are more prone to painful CMC arthritis. Understanding this connection could improve the diagnosis and treatment of hand problems. This study focuses on gathering information rather than testing the effectiveness of a specific treatment.

Who Is on the Research Team?

CM

Chris Mulligan

Principal Investigator

Russell Sage College

Are You a Good Fit for This Trial?

This trial is for men and women aged 35 to 89 who have been diagnosed with thumb carpometacarpal (CMC) arthritis and have tried non-surgical treatments. It's not open to individuals under 35, over 89, or prisoners.

Inclusion Criteria

I have been diagnosed with thumb arthritis.
I am either male or female.
I am younger than 89 years old.
See 2 more

Exclusion Criteria

Prisoners
I am younger than 35 years old.
I am 90 years old or older.

Timeline for a Trial Participant

Screening

Participants are screened for eligibility to participate in the trial

1 visit
1 visit (in-person)

Clinical Examination

Participants undergo a clinical examination to identify the presence of the Linburg-Comstock Variation (LCV)

10 seconds
1 visit (in-person)

Data Collection

Demographic and dichotomous data are collected to determine the presence of LCV in one or both hands

Up to 2 years

Follow-up

Participants are informed of their LCV status during the clinical examination

Immediate

What Are the Treatments Tested in This Trial?

Interventions

  • Descriptive
Trial Overview The study is descriptive and aims to investigate the prevalence of Linburg-Comstock Variation (LCV), a tendon connection in the wrist, among patients with CMC arthritis to see if there's an association between LCV and painful CMC arthritis.
How Is the Trial Designed?
1Treatment groups
Experimental Treatment
Group I: Positive LCVExperimental Treatment1 Intervention

Find a Clinic Near You

Who Is Running the Clinical Trial?

Russell Sage College

Lead Sponsor

Trials
3
Recruited
580+

Albany Medical College

Collaborator

Trials
96
Recruited
12,700+
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