Reducose for Menopause
(CALM-R Trial)
What You Need to Know Before You Apply
What is the purpose of this trial?
The purpose of this double-blind, randomized, placebo-controlled trial is to. evaluate daily Reducose® (mulberry leaf extract) supplementation taken with the two largest meals for 12 weeks on improving glycemic response and perimenopausal symptoms in women aged 40-60 years. Glycemic response is measured using Dexcom Stelo continuous glucose monitors during standardized test meals, and menopausal symptoms and sleep/quality-of-life outcomes are assessed using validated surveys administered through the Chloe app in a decentralized U.S. study.
Are You a Good Fit for This Trial?
This trial is for women aged 40-60 who are experiencing menopausal symptoms and have a BMI of 18.5 to 35 kg/m2. They should be weight stable, not on hormone replacement therapy, and must have had a recent health check with normal diabetes markers. Participants need access to a smartphone to use specific apps.Inclusion Criteria
Timeline for a Trial Participant
Screening
Participants are screened for eligibility to participate in the trial
Treatment
Participants receive daily Reducose® supplementation with the two largest meals for 12 weeks
Follow-up
Participants are monitored for safety and effectiveness after treatment
What Are the Treatments Tested in This Trial?
Interventions
- Reducose®
Trial Overview
The CALM-R study tests if Reducose® (mulberry leaf extract) can improve blood sugar control and ease menopause symptoms when taken with meals over 12 weeks. It's compared against a placebo in this double-blind study using continuous glucose monitoring and surveys.
How Is the Trial Designed?
2
Treatment groups
Experimental Treatment
Placebo Group
Find a Clinic Near You
Who Is Running the Clinical Trial?
Phynova Group Ltd
Lead Sponsor
People Science
Collaborator
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