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Pressure Changes for Open-Angle Glaucoma

N/A

Recruiting

Led By Harry A Quigley, MD

Research Sponsored by Johns Hopkins University

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Be older than 18 years old

Timeline

Screening 3 weeks

Treatment Varies

Follow Up up to 2 months

Awards & highlights

Study Summary

This trial looks at how well the lamina cribrosa, a part of the eye, responds to changes in pressure.

Who is the study for?

This trial is for individuals with open-angle glaucoma who are willing to drink water and undergo imaging tests. It's not suitable for those who do not consent to these procedures or cannot be imaged.Check my eligibility

What is being tested?

The study is examining how the depth of a part of the eye called the lamina cribrosa changes when eye pressure varies. Participants will either wear swimming goggles or undergo a procedure called laser suturelysis.See study design

What are the potential side effects?

Potential side effects may include discomfort from wearing goggles, temporary vision changes, or eye irritation. The laser procedure could cause redness, mild pain, or temporary increased eye pressure.

Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ up to 2 months

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~up to 2 months

This trial's timeline: 3 weeks for screening, Varies for treatment, and up to 2 months for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.

Primary outcome measures

Change in anterior lamina cribrosa depth

Trial Design

1Treatment groups

Experimental Treatment

Group I: persons drinking waterExperimental Treatment1 Intervention

all persons in the study will have images of the eye at baseline eye pressure, then the intervention will be to drink 2 bottles of water to increase eye pressure or decrease eye pressure, then will have images taken a second time

Do I qualify?Apply below to find out

Find a Location

Who is running the clinical trial?

Johns Hopkins UniversityLead Sponsor

2,260 Previous Clinical Trials

14,820,580 Total Patients Enrolled

Harry A Quigley, MDPrincipal InvestigatorProfessor

1 Previous Clinical Trials

92 Total Patients Enrolled

Media Library

Laser Suturelysis Clinical Trial Eligibility Overview. Trial Name: NCT03267849 — N/A

Open-Angle Glaucoma Research Study Groups: persons drinking water

Open-Angle Glaucoma Clinical Trial 2023: Laser Suturelysis Highlights & Side Effects. Trial Name: NCT03267849 — N/A

Laser Suturelysis 2023 Treatment Timeline for Medical Study. Trial Name: NCT03267849 — N/A

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Are any slots left for participants in this clinical trial?

"Indeed, the trial is still open for participation. The study was first listed on clinicaltrials.gov in July 1st 2017 and most recently updated five days ago."

Answered by AI

What is the cap for patient participation in this research trial?

"Affirmative. Details on clinicaltrials.gov demonstrate that this trial is currently accepting participants, having been initially posted on July 1st 2017 and last updated 5 days ago. Two medical facilities are seeking 200 individuals to take part in the research project."

Answered by AI

Are the elderly being included in the experiment?

"This medical study is accepting applicants that are over the age of 21 and below a century old."

Answered by AI

What specific criteria must be met to participate in this research?

"The prerequisites for this medical experiment are open-angle glaucoma and an age between 21 and 100. The objective is to enrol 200 individuals in the trial."

Answered by AI

Recent research and studies

Ophthalmology GlaucomaJournal

The Strain Response to Intraocular Pressure Decrease in the Lamina Cribrosa of Patients with Glaucoma

Czerpak, Cameron A., Michael Saheb Kashaf, Brandon K. Zimmerman, Harry A. Quigley, and Thao D. Nguyen. 2022. “The Strain Response to Intraocular Pressure Decrease in the Lamina Cribrosa of Patients with Glaucoma”. Ophthalmology Glaucoma. Elsevier BV. doi:10.1016/j.ogla.2022.07.005.

clinicaltrials.govStudy

Lamina Cribrosa Depth Change With Change in Eye Pressure

2017. "Lamina Cribrosa Depth Change With Change in Eye Pressure". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT03267849.