← Back to Search

Behavioral Intervention

Cognitive Behavioral Therapy for Gastrointestinal Stromal Tumor (GIST-MAAT Trial)

N/A

Recruiting

Led By Robert J Ferguson, PhD

Research Sponsored by University of Pittsburgh

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Report cognitive problems of memory and concentration attributed to GIST and/or treatment with a score of 10 or below on the FACT-Cog Impact on Quality of Life Scale

Age 18 and above

Timeline

Screening 3 weeks

Treatment Varies

Follow Up after 8 weekly maat visits (or up to 12 weeks if weekly visits are rescheduled)

Awards & highlights

GIST-MAAT Trial Summary

This trial will help to determine if MAAT is an effective treatment for CRCI in people with gastrointestinal stromal tumors.

Who is the study for?

This trial is for adults over 18 with gastrointestinal stromal tumors (GIST) who have had at least a year of TKI therapy and are experiencing memory and concentration issues. Participants must speak English, consent to the study, be willing to use videoconferencing for sessions, and not have severe mental disorders or a history of certain cancer treatments.Check my eligibility

What is being tested?

The trial is testing Memory and Attention Adaptation Training (MAAT), a type of cognitive-behavioral therapy delivered via videoconference aimed at reducing cognitive impairments in GIST patients. It evaluates the effectiveness on self-reported cognitive issues as well as objective neuropsychological tests.See study design

What are the potential side effects?

Since MAAT involves psychological training rather than medication, typical drug side effects aren't expected. However, participants may experience fatigue or emotional discomfort during the cognitive exercises.

GIST-MAAT Trial Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below

Select...

I experience memory and concentration issues due to my GIST treatment, scoring 10 or below on the FACT-Cog.

Select...

I am 18 years old or older.

Select...

I have been diagnosed with a gastrointestinal stromal tumor.

GIST-MAAT Trial Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ after 8 weekly maat visits (or up to 12 weeks if weekly visits are rescheduled)

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~after 8 weekly maat visits (or up to 12 weeks if weekly visits are rescheduled)

This trial's timeline: 3 weeks for screening, Varies for treatment, and after 8 weekly maat visits (or up to 12 weeks if weekly visits are rescheduled) for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.

Primary outcome measures

California Verbal Learning Test-3 (CVLT-3)

Controlled Oral World Association Test (COWAT)

Symbol Digit Modalities Test (SDMT)

Secondary outcome measures

FACT-Cog PCI

PROMIS Item Bank -Emotional Distress - Short Form 8a

PROMIS Item Bank: Anxiety- Short Form 8a.

+2 more

GIST-MAAT Trial Design

1Treatment groups

Experimental Treatment

Group I: Memory and Attention Adaptation Training (MAAT)Experimental Treatment1 Intervention

A cognitive-behavioral therapy (CBT) designed for the treatment of Cancer-Related Cognitive Impairment (CRCI)

0 / 3Eligibility criteria met

Find a Location

Who is running the clinical trial?

University of PittsburghLead Sponsor

1,720 Previous Clinical Trials

16,342,781 Total Patients Enrolled

Robert J Ferguson, PhDPrincipal Investigator - University of Pittsburgh School of Medicine, UPMC Hillman Cancer Center

University of Pittsburgh

Anette U Duensing, MDPrincipal InvestigatorUniversity of Pittsburgh School of Medicine, UPMC Hillman Cancer Center

Media Library

Memory and Attention Adaptation Training (MAAT) (Behavioral Intervention) Clinical Trial Eligibility Overview. Trial Name: NCT04879979 — N/A

Gastrointestinal Stromal Tumor Research Study Groups: Memory and Attention Adaptation Training (MAAT)

Gastrointestinal Stromal Tumor Clinical Trial 2023: Memory and Attention Adaptation Training (MAAT) Highlights & Side Effects. Trial Name: NCT04879979 — N/A

Memory and Attention Adaptation Training (MAAT) (Behavioral Intervention) 2023 Treatment Timeline for Medical Study. Trial Name: NCT04879979 — N/A

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

What are the projected results of this experiment?

"The primary measured outcome of this study, which will be tracked over 8 (or up to 12) weekly MAAT visits, is the Controlled Oral Word Association Test (COWAT). Secondary objectives include a PROMIS Item Bank analysis on Anxiety- Short Form 8a., FACT-Cog PCI and PROMIS Item Bank -Emotional Distress - Short Form 8a. These assessments use 5- point Likert ratings that produce four distinct scales: Quality of life, Cognitive Impairments, Comments from Others and Perceived Abilities; while emotional distress results are indicated by higher scores."

Answered by AI

How many individuals are currently involved in this clinical experiment?

"Indeed, the data accessible via clinicaltrials.gov confirms that this research endeavour is on-going and recruiting participants. The study was first published on December 1st 2021 and recently revised on April 15th 2022; 30 candidates are sought from a single site to partake in the trial."

Answered by AI

Is enrollment currently being accepted for this experiment?

"This investigation is currently recruiting, with the initial trial post being published on December 1st 2021 and an update as recent as April 15th 2022."

Answered by AI

Recent research and studies

clinicaltrials.govStudy

GIST and Memory and Attention Adaptation Training

Robert J Ferguson, PhD 2021. "GIST and Memory and Attention Adaptation Training". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT04879979.