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Respiratory Support

30 L for Fluid Overload

N/A
Waitlist Available
Research Sponsored by Nova Scotia Health Authority
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be between 18 and 65 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up 3 minutes after the intervention
Awards & highlights

Study Summary

This trial is testing whether using high-flow nasal cannula (HFNC) affects the size of the inferior vena cava (IVC) as measured by point-of-care ultrasound, in patients who are critically ill.

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~3 minutes after the intervention
This trial's timeline: 3 weeks for screening, Varies for treatment, and 3 minutes after the intervention for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Inferior vena cava maximal diameter in millimeter
Secondary outcome measures
Inferior vena cava maximal collapsibility index

Trial Design

3Treatment groups
Active Control
Placebo Group
Group I: 30 LActive Control1 Intervention
The HFNC flow will be set at 30 L / min. The IVC size will then be assessed using a POCUS
Group II: 60 LActive Control1 Intervention
The HFNC flow will be set at 60 L / min. The IVC size will then be assessed using a POCUS
Group III: 0 LPlacebo Group1 Intervention
This will be the arm where the baseline IVC assessment size is conducted at

Find a Location

Who is running the clinical trial?

Nova Scotia Health AuthorityLead Sponsor
258 Previous Clinical Trials
83,809 Total Patients Enrolled

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Does this clinical experiment accept new participants at the moment?

"The information available on clinicaltrials.gov highlights that this trial is no longer recruiting patients; it was initially posted on July 1st 2022 and the last update took place in March 2nd 2022. Nonetheless, there are 10 other trials actively taking partakers at present."

Answered by AI

Could I be considered for this research project?

"This trial is looking for 45 individuals aged 18 to 40 who suffer from fluid overload. To qualify, aspiring patients must be able to walk and meet the age requirement of between 18 and 40 years old."

Answered by AI

Does this experiment accommodate those aged sixty years or older?

"This clinical trial requires participants to have an age range of 18-40 years old; however, there are 9 total studies that accommodate individuals under the age threshold and over 65."

Answered by AI
Recent research and studies
New England Journal of MedicineJournal
Comparison of Two Fluid-management Strategies in Acute Lung Injury
“Comparison of Two Fluid-management Strategies in Acute Lung Injury”. 2006. “Comparison of Two Fluid-management Strategies in Acute Lung Injury”. New England Journal of Medicine. Massachusetts Medical Society. doi:10.1056/nejmoa062200.
Journal of the American Society of EchocardiographyJournal
Guidelines for the Echocardiographic Assessment of the Right Heart in Adults: A Report from the American Society of Echocardiography
Rudski, Lawrence G., Wyman W. Lai, Jonathan Afilalo, Lanqi Hua, Mark D. Handschumacher, Krishnaswamy Chandrasekaran, Scott D. Solomon, Eric K. Louie, and Nelson B. Schiller. 2010. “Guidelines for the Echocardiographic Assessment of the Right Heart in Adults: A Report from the American Society of Echocardiography”. Journal of the American Society of Echocardiography. Elsevier BV. doi:10.1016/j.echo.2010.05.010.
Respiratory CareJournal
Effect of Very-high-flow Nasal Therapy on Airway Pressure and End-expiratory Lung Impedance in Healthy Volunteers
Parke, R. L., A. Bloch, and S. P. McGuinness. 2015. “Effect of Very-high-flow Nasal Therapy on Airway Pressure and End-expiratory Lung Impedance in Healthy Volunteers”. Respiratory Care. Daedalus Enterprises. doi:10.4187/respcare.04028.
Emergency Medicine Clinics of North AmericaJournal
The RUSH Exam: Rapid Ultrasound in Shock in the Evaluation of the Critically Lll
Perera, Phillips, Thomas Mailhot, David Riley, and Diku Mandavia. 2010. “The RUSH Exam: Rapid Ultrasound in Shock in the Evaluation of the Critically Lll”. Emergency Medicine Clinics of North America. Elsevier BV. doi:10.1016/j.emc.2009.09.010.
~16 spots leftby Apr 2025
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