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Dynamic Contrast-Enhanced Ultrasound Imaging for Liver Cirrhosis

N/A
Waitlist Available
Led By Andrej Lyshchik, MD, PhD
Research Sponsored by Sidney Kimmel Cancer Center at Thomas Jefferson University
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up up to 12 months
Awards & highlights

Study Summary

This trial looks at how well ultrasound works in diagnosing liver cancer in patients with cirrhosis. It may help find and diagnose liver cancer.

Eligible Conditions
  • Liver Cirrhosis

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~up to 12 months
This trial's timeline: 3 weeks for screening, Varies for treatment, and up to 12 months for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Negative Predictive Value of contrast-enhanced ultrasound evaluation (CEUS) for diagnosis of Hepatocellular cancer using a 95% confidence interval
Positive Predictive Value of contrast-enhanced ultrasound evaluation (CEUS) for diagnosis of Hepatocellular cancer using a 95% confidence interval
Sensitivity of contrast-enhanced ultrasound evaluation (CEUS) for diagnosis of Hepatocellular cancer using a 95% confidence interval 95% confidence interval for HCC diagnosis using CEUS LR-5 classification
+1 more

Trial Design

1Treatment groups
Experimental Treatment
Group I: Diagnostic Contrast-Enhanced Ultrasound Imaging (CEUS)Experimental Treatment1 Intervention
Patients receive sulfur hexafluoride IV and undergo CEUS imaging over 10 minutes.
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
Dynamic Contrast-Enhanced Ultrasound Imaging
2018
Completed Phase 1
~630

Find a Location

Who is running the clinical trial?

Sidney Kimmel Cancer Center at Thomas Jefferson UniversityLead Sponsor
162 Previous Clinical Trials
10,299 Total Patients Enrolled
National Cancer Institute (NCI)NIH
13,665 Previous Clinical Trials
40,925,242 Total Patients Enrolled
16 Trials studying Liver Cirrhosis
11,121 Patients Enrolled for Liver Cirrhosis
GE HealthcareIndustry Sponsor
290 Previous Clinical Trials
630,459 Total Patients Enrolled

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.
Recent research and studies
clinicaltrials.govStudy
Contrast-Enhanced Ultrasound Imaging in Diagnosing Liver Cancer in Patients With Cirrhosis
2018. "Contrast-Enhanced Ultrasound Imaging in Diagnosing Liver Cancer in Patients With Cirrhosis". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT03318380.
~84 spots leftby Apr 2025
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