Restrictive Transfusion Arm for Anemia

University of Chicago, Chicago, IL
Anemia+4 More ConditionsRed blood cell transfusion - Other
Eligibility
18+
All Sexes
What conditions do you have?
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Study Summary

This trial is testing whether restrictive transfusions (at Hb<7g/dL) are as effective as liberal transfusions (at Hb<9g/dL) in reducing fatigue and improving activity levels in hospitalized patients with anemia.

Eligible Conditions
  • Anemia
  • Fatigue
  • Physical Function
  • Blood Transfusion

Treatment Effectiveness

Study Objectives

1 Primary · 3 Secondary · Reporting Duration: Fatigue will be measured at admission to the hospital during the index hospitalization and 7 days after hospital discharge.

Day 7
Change in 6 Minute Walk Test (6MWT) distance
Day 7
Change in self-reported activity level
Day 7
Change in self-reported fatigability level
Day 7
Change in self-reported fatigue level

Trial Safety

Awards & Highlights

No Placebo Group
All patients enrolled in this trial will receive the new treatment.

Trial Design

2 Treatment Groups

Restrictive Transfusion Arm
1 of 2
Liberal Transfusion Arm
1 of 2

Active Control

748 Total Participants · 2 Treatment Groups

Primary Treatment: Restrictive Transfusion Arm · No Placebo Group · N/A

Restrictive Transfusion Arm
Other
ActiveComparator Group · 1 Intervention: Red blood cell transfusion · Intervention Types: Other
Liberal Transfusion Arm
Other
ActiveComparator Group · 1 Intervention: Red blood cell transfusion · Intervention Types: Other

Trial Logistics

Trial Timeline

Screening: ~3 weeks
Treatment: Varies
Reporting: fatigue will be measured at admission to the hospital during the index hospitalization and 7 days after hospital discharge.

Who is running the clinical trial?

University of ChicagoLead Sponsor
950 Previous Clinical Trials
759,528 Total Patients Enrolled

Eligibility Criteria

Age 18+ · All Participants · 0 Total Inclusion Criteria

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Frequently Asked Questions

Is this experiment searching for new participants at present?

"Affirmative. Data on clinicaltrials.gov affirms that this study, which was first publicized in February of 2022, is still actively searching for participants. There are 748 available slots at a single medical facility." - Anonymous Online Contributor

Unverified Answer

What is the overall participation rate for this experiment?

"Affirmative. The online record on clinicaltrials.gov confirms that this research has been luring participants since February 1st 2022 and was most recently updated May 16th 2022. Altogether, 748 subjects are expected to join the study from a single trial centre." - Anonymous Online Contributor

Unverified Answer
Please Note: These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.