← Back to Search

Vestibular Therapy for Alzheimer's Disease

N/A

Recruiting

Led By Yuri Agrawal, MD

Research Sponsored by Johns Hopkins University

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Diagnosis of AD based on the National Institute on Aging-Alzheimer Association 2011 criteria that is mild-moderate (CDR=0.5-2)

Age ≥ 60 years

Timeline

Screening 3 weeks

Treatment Varies

Follow Up 1 year

Awards & highlights

Study Summary

This trial will study whether vestibular therapy, which is known to improve balance in healthy adults, can also reduce falls in patients with Alzheimer's disease.

Who is the study for?

This trial is for people over 60 with mild-to-moderate Alzheimer's who have balance issues due to inner ear problems. They need a caregiver available and must be able to do certain tests and therapy sessions. Those with severe Alzheimer's, other dementias, or conditions that limit participation (like needing a cane) can't join.Check my eligibility

What is being tested?

The study is testing if vestibular therapy, which helps improve balance by focusing on the inner ear system, can reduce falls in Alzheimer's patients. Participants will either receive this special therapy or an active control treatment in a randomized setup.See study design

What are the potential side effects?

Vestibular physical therapy generally has minimal side effects but may include temporary dizziness or nausea during exercises designed to address balance disorders.

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below

Select...

I have been diagnosed with mild to moderate Alzheimer's disease.

Select...

I am 60 years old or older.

Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ 1 year

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~1 year

This trial's timeline: 3 weeks for screening, Varies for treatment, and 1 year for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.

Primary outcome measures

Number of participant falls

Trial Design

2Treatment groups

Experimental Treatment

Active Control

Group I: Vestibular therapyExperimental Treatment1 Intervention

Vestibular therapy (Vestibular physical therapy) entails an 8-week course of exercises delivered by a physical therapist designed to improve vestibular function.

Group II: Active controlActive Control1 Intervention

The active control regimen consists of eye movement exercises (e.g. smooth pursuit eye movements) and also general conditioning exercises (e.g. range of motion exercises, lifting light weights with the arms and legs). This regimen is "vestibular neutral" in that head movements which specifically challenge the vestibular system are avoided.

0 / 2Eligibility criteria met

Find a Location

Who is running the clinical trial?

Johns Hopkins UniversityLead Sponsor

2,262 Previous Clinical Trials

14,823,064 Total Patients Enrolled

National Institute on Aging (NIA)NIH

1,672 Previous Clinical Trials

28,018,563 Total Patients Enrolled

Yuri Agrawal, MDPrincipal InvestigatorJohns Hopkins University

Media Library

Active control Clinical Trial Eligibility Overview. Trial Name: NCT03799991 — N/A

Alzheimer's Disease Research Study Groups: Vestibular therapy, Active control

Alzheimer's Disease Clinical Trial 2023: Active control Highlights & Side Effects. Trial Name: NCT03799991 — N/A

Active control 2023 Treatment Timeline for Medical Study. Trial Name: NCT03799991 — N/A

Alzheimer's Disease Patient Testimony for trial: Trial Name: NCT03799991 — N/A

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

What is the total number of subjects participating in this research?

"Affirmative. Clinicaltrials.gov hosts information confirming that this medical trial is seeking participants, which began recruiting on March 1st 2021 and was last updated in December of the same year. A total of 100 patients are being recruited from one location."

Answered by AI

Is the enrollment process open for this investigation?

"As visible on clinicaltrials.gov, the recruitment for this medical trial is still active; it was initially published in March 2021 and its details were most recently modified December of that same year."

Answered by AI