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Eye Patching + Prism Adaptation for Strabismus (DESDEE Trial)

N/A

Recruiting

Research Sponsored by University of Rochester

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

No prior strabismus surgery

No diagnosis of dissociated vertical deviation

Timeline

Screening 3 weeks

Treatment Varies

Follow Up 2 weeks

Awards & highlights

DESDEE Trial Summary

This trial is testing if a type of eye crossing can be changed with patching or prism adaptation.

Who is the study for?

This trial is for children under 18 with a specific eye alignment issue called divergence excess exotropia. They must be able to participate in testing, have normal neurological function (except ADHD or autism if they can still cooperate), and have good vision (20/40 or better). Kids who've had previous eye surgery or other types of strabismus aren't eligible.Check my eligibility

What is being tested?

The study is looking at how effective two methods are in treating an eye condition where the eyes drift outward. One method involves covering one eye with a patch for 24 hours, while the other uses special lenses called prisms to correct the misalignment temporarily.See study design

What are the potential side effects?

Patching might cause discomfort, skin irritation around the patched area, or temporary changes in vision. Prism adaptation may lead to eyestrain, headaches, dizziness, or nausea as eyes adjust to prism correction.

DESDEE Trial Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below

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I have never had surgery for crossed eyes.

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I have not been diagnosed with dissociated vertical deviation.

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I have been diagnosed with a specific type of eye misalignment called divergence excess exotropia.

DESDEE Trial Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ 2 weeks

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~2 weeks

This trial's timeline: 3 weeks for screening, Varies for treatment, and 2 weeks for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.

Primary outcome measures

Percent of participants reclassified as divergence excess exotropia

Percent of participants reclassified as simulated divergence excess exotropia

DESDEE Trial Design

2Treatment groups

Experimental Treatment

Group I: Prism AdaptationExperimental Treatment1 Intervention

Group II: PatchingExperimental Treatment1 Intervention

Treatment

First Studied

Drug Approval Stage

How many patients have taken this drug

Patching

2005

Completed Phase 3

~650

Prism Adaptation

2015

N/A

~30

0 / 3Eligibility criteria met

Find a Location

Who is running the clinical trial?

University of RochesterLead Sponsor

840 Previous Clinical Trials

534,175 Total Patients Enrolled

Media Library

Patching Clinical Trial Eligibility Overview. Trial Name: NCT05242510 — N/A

Strabismus Research Study Groups: Patching, Prism Adaptation

Strabismus Clinical Trial 2023: Patching Highlights & Side Effects. Trial Name: NCT05242510 — N/A

Patching 2023 Treatment Timeline for Medical Study. Trial Name: NCT05242510 — N/A

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

What is the present-day coverage of this experiment?

"Patients can enrol in this trial at Ross Eye Institute located in Buffalo, New york; University of Rochester Medical Centre situated in Rochester, Pennsylvania; and the University of Pittsburgh found in Pittsburgh, Ontario. Additionally, there are 6 other medical sites hosting enrollment for this clinical study."

Answered by AI

Does this experiment still have slots open for participants?

"As evidenced on clinicaltrials.gov, this medical trial is no longer recruiting patients as of September 10th 2022. Although the study has stopped its recruitment efforts, there are still 7 other trials that are actively looking for potential candidates."

Answered by AI

Recent research and studies

clinicaltrials.govStudy

Evaluation of Exotropia After Patching the Eye or After Prism Adaptation

Matthew Gearinger 2024. "Evaluation of Exotropia After Patching the Eye or After Prism Adaptation". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT05242510.