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Procedure

Intervention for Esophageal Achalasia

N/A
Waitlist Available
Led By Eran Shlomovitz, MD
Research Sponsored by University Health Network, Toronto
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up 1 year
Awards & highlights

Study Summary

This study evaluates the efficacy and safety of the Per-Oral Endoscopic Myotomy (POEM) technique for lower esophageal sphincter myotomy in patients suffering from spastic esophageal disorders such as achalasia at a Canadian institution. The investigators hypothesize that POEM is a safe and effective technique for the surgical management of such disorders at our institution.

Eligible Conditions
  • Esophageal Achalasia

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~1 year
This trial's timeline: 3 weeks for screening, Varies for treatment, and 1 year for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Effectiveness of intervention (Symptom severity relief according to pre- and post-operative quality of life questionnaire)
Secondary outcome measures
Diameter of the esophageal body
LES pressure (according to manometry)
Surgical complications
+1 more

Trial Design

1Treatment groups
Experimental Treatment
Group I: InterventionExperimental Treatment1 Intervention
Patients undergoing POEM for spastic esophageal disorders such as achalasia at the University Health Network, Toronto, Canada
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
POEM
2015
N/A
~140

Find a Location

Who is running the clinical trial?

University Health Network, TorontoLead Sponsor
1,468 Previous Clinical Trials
484,469 Total Patients Enrolled
1 Trials studying Esophageal Achalasia
56 Patients Enrolled for Esophageal Achalasia
Eran Shlomovitz, MDPrincipal InvestigatorUniversity Health Network, Toronto

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.
Recent research and studies
EndoscopyJournal
Peroral Endoscopic Myotomy (POEM) for Esophageal Achalasia
Inoue, H., H. Minami, Y. Kobayashi, Y. Sato, M. Kaga, M. Suzuki, H. Satodate, N. Odaka, H. Itoh, and S. Kudo. 2010. “Peroral Endoscopic Myotomy (POEM) for Esophageal Achalasia”. Endoscopy. Georg Thieme Verlag KG. doi:10.1055/s-0029-1244080.
Annals of SurgeryJournal
Classification of Surgical Complications
Dindo, Daniel, Nicolas Demartines, and Pierre-Alain Clavien. 2004. “Classification of Surgical Complications”. Annals of Surgery. Ovid Technologies (Wolters Kluwer Health). doi:10.1097/01.sla.0000133083.54934.ae.
EndoscopyJournal
Submucosal Endoscopic Esophageal Myotomy: A Novel Experimental Approach for the Treatment of Achalasia
Pasricha, P., R. Hawari, I. Ahmed, J. Chen, P. Cotton, R. Hawes, A. Kalloo, S. Kantsevoy, and C. Gostout. 2007. “Submucosal Endoscopic Esophageal Myotomy: A Novel Experimental Approach for the Treatment of Achalasia”. Endoscopy. Georg Thieme Verlag KG. doi:10.1055/s-2007-966764.
The Annals of Thoracic SurgeryJournal
Outcomes After Minimally Invasive Esophagomyotomy
Luketich, James D, Hiran C Fernando, Neil A Christie, Percival O Buenaventura, Robert J Keenan, Sayeed Ikramuddin, and Philip R Schauer. 2001. “Outcomes After Minimally Invasive Esophagomyotomy”. The Annals of Thoracic Surgery. Elsevier BV. doi:10.1016/s0003-4975(01)03127-7.
~5 spots leftby Apr 2025
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