212 Participants Needed

Outcomes for Endometrial Cancer

Recruiting at 23 trial locations
CT
Overseen ByClinical Trials Referral Office
Age: Any Age
Sex: Any
Trial Phase: Academic
Sponsor: Mayo Clinic
No Placebo GroupAll trial participants will receive the active study treatment (no placebo)

What You Need to Know Before You Apply

What is the purpose of this trial?

This trial examines how tiny tumor cells in the lymph nodes (small glands that help fight infection) might provide clues about the future health of individuals with a certain type of low-risk uterine cancer. Researchers aim to determine if these cell findings can predict outcomes without requiring extra treatment after surgery. Individuals who have undergone surgery for low-risk endometrial cancer, had their lymph nodes checked, and have not received additional cancer treatments might be suitable for this study. As a Phase 3 trial, this study represents the final step before FDA approval, offering participants a chance to contribute to a potentially groundbreaking treatment.

Will I have to stop taking my current medications?

The trial information does not specify whether you need to stop taking your current medications. It's best to discuss this with the trial coordinators or your doctor.

Why are researchers excited about this trial?

Researchers are excited about this trial because it aims to shed light on the significance of isolated tumor cells in the sentinel lymph nodes for patients with low-risk endometrial cancer. Unlike traditional treatments that focus solely on removing cancerous tissues and lymph nodes, this trial emphasizes understanding how these isolated cells might impact patient outcomes. The insights gained could potentially refine current treatment strategies and help tailor more personalized approaches, improving long-term prognosis for patients.

Who Is on the Research Team?

GE

Gretchen E. Glaser, MD

Principal Investigator

Mayo Clinic in Rochester

Are You a Good Fit for This Trial?

Inclusion Criteria

I am willing to skip additional treatment after the main treatment.
My endometrial cancer is low-risk, early stage, and has minimal spread to blood vessels.
I've had complete surgical staging for cancer as per guidelines.
See 2 more

Timeline for a Trial Participant

Screening

Participants are screened for eligibility to participate in the trial

2-4 weeks

Observational

Patients undergo tissue sample collection and have their medical records reviewed

Up to 5 years

Follow-up

Participants are monitored for recurrence-free survival and overall survival

Up to 5 years

What Are the Treatments Tested in This Trial?

Interventions

  • Non-Interventional Study
How Is the Trial Designed?
1Treatment groups
Experimental Treatment
Group I: ObservationalExperimental Treatment1 Intervention

Find a Clinic Near You

Who Is Running the Clinical Trial?

Mayo Clinic

Lead Sponsor

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