Tape Stripping for Hand Eczema
What You Need to Know Before You Apply
What is the purpose of this trial?
This trial aims to better understand chronic hand eczema and atopic dermatitis by using noninvasive methods like tape stripping, a technique to collect skin samples, to study the skin. Researchers seek to observe how these skin conditions change over time and affect quality of life. Participants include those with moderate to severe chronic hand eczema or atopic dermatitis, as well as healthy volunteers. Ideal candidates have experienced either chronic hand eczema or atopic dermatitis for at least six months and have significant symptoms. As an unphased trial, this study offers participants the opportunity to contribute to groundbreaking research that could enhance understanding and treatment of these skin conditions.
Do I need to stop my current medications for the trial?
Yes, you may need to stop certain medications before joining the trial. For example, you cannot use systemic antibiotics within 2 weeks, topical antibiotics within 1 week, or certain topical treatments like corticosteroids within 1 week before the trial starts. There are also specific restrictions for medications affecting chronic hand eczema and atopic dermatitis.
What prior data suggests that these noninvasive molecular and imaging techniques are safe?
Research has shown that tape stripping is a safe and well-tolerated method in skin research. Studies have found that it gathers important information about skin conditions like chronic hand eczema and atopic dermatitis with minimal discomfort or side effects. This technique is minimally invasive, as it does not involve cutting or breaking the skin, which reduces the risk of complications.
Studies using tape stripping for skin analysis have reported no major negative effects, suggesting the method is generally safe for participants. Concerns about the treatment should be discussed with the trial team or a doctor.12345Why are researchers excited about this trial?
Tape stripping is unique because it offers a new technique for managing chronic hand eczema by gently removing the top layer of the skin. Unlike typical treatments like creams and ointments that only address symptoms on the surface, tape stripping helps researchers gain deeper insights into the skin's condition and how it responds to treatment at the molecular level. This method is non-invasive and can provide valuable information quickly, which excites researchers about its potential to improve understanding and treatment of skin conditions.
What evidence suggests that tape stripping is effective for chronic hand eczema and atopic dermatitis?
This trial will use tape stripping to study chronic hand eczema (CHE) and atopic dermatitis (AD). Research has shown that tape stripping is a promising method for gaining insights into these conditions. Studies have found that tape stripping can detect specific changes in the skin's immune system and protective barrier. This method uncovers unique biological markers, enhancing understanding of these conditions. For both CHE and AD, tape stripping has successfully identified skin issues and potential treatment targets. While this technique focuses on understanding rather than treating the conditions, it could lead to more personalized treatments in the future.56789
Who Is on the Research Team?
Robert Bissonnette, MD, MSc
Principal Investigator
Innovaderm Research Inc.
Are You a Good Fit for This Trial?
Inclusion Criteria
Timeline for a Trial Participant
Screening
Participants are screened for eligibility to participate in the trial
Characterization
Characterize differences in skin morphological parameters and molecular signatures using noninvasive techniques
Biobanking
Collection and storage of biological samples for future research
Follow-up
Participants are monitored for changes in disease severity and quality of life
What Are the Treatments Tested in This Trial?
Interventions
- Tape Stripping
Find a Clinic Near You
Who Is Running the Clinical Trial?
Dr. Robert Bissonnette
Lead Sponsor