TDCS for Spasmodic Dysphonia
Trial Summary
Do I need to stop my current medications for the trial?
The trial information does not specify whether you need to stop taking your current medications.
How does the treatment TDCS differ from other treatments for spasmodic dysphonia?
TDCS (transcranial direct current stimulation) is unique because it is a non-invasive treatment that uses a mild electrical current to stimulate specific areas of the brain, potentially offering a new approach compared to the standard botulinum toxin injections, which require repeated administration and can lose effectiveness over time.12345
What is the purpose of this trial?
This project will apply transcranial direct current stimulation (tDCS) to multiple brain areas to evaluate the effects as a potential treatment for laryngeal dystonia (formerly spasmodic dysphonia).
Research Team
Nabin Koirala, PhD
Principal Investigator
Yale University
Eligibility Criteria
This trial is for individuals with laryngeal dystonia, a voice disorder, who have no other speech or voice disorders and are not pregnant. They must be willing to follow the study procedures for its duration and either have been clinically evaluated for LD or have proof of diagnosis (controls exempted). People with epilepsy, depression, or claustrophobia cannot participate.Inclusion Criteria
Exclusion Criteria
Timeline
Screening
Participants are screened for eligibility to participate in the trial
Baseline Assessment
Baseline neuroimaging data acquired via MRI, EEG
Treatment
Participants undergo HD-tDCS Stimulation for twenty minutes while watching videos/movies or performing a word production task
Follow-up
Participants are monitored for safety and effectiveness after treatment
Treatment Details
Interventions
- TDCS
Find a Clinic Near You
Who Is Running the Clinical Trial?
Yale University
Lead Sponsor
National Spasmodic Dysphonia Association
Collaborator