RAPIDS Intervention for Drug Overdose

Phase-Based Progress Estimates
1
Effectiveness
1
Safety
Drug Overdose+2 More
RAPIDS Intervention - Behavioral
Eligibility
18+
All Sexes
What conditions do you have?
Select

Study Summary

This trial will test a new way to prevent overdoses among people who use drugs, by incorporating rapid fentanyl testing into an educational intervention. The goal is to reduce rates of overdose compared to standard education and naloxone distribution.

Eligible Conditions
  • Drug Overdose
  • Opioids

Treatment Effectiveness

Effectiveness Progress

1 of 3

Study Objectives

1 Primary · 1 Secondary · Reporting Duration: 12 months post-randomization

12 months post-randomization
Accidental non-fatal overdose in the past month
The number of fatal overdose events

Trial Safety

Safety Progress

1 of 3

Trial Design

2 Treatment Groups

Standard OEND
1 of 2
RAPIDS intervention
1 of 2

Active Control

Experimental Treatment

500 Total Participants · 2 Treatment Groups

Primary Treatment: RAPIDS Intervention · No Placebo Group · N/A

RAPIDS interventionExperimental Group · 2 Interventions: RAPIDS Intervention, Standard OEND · Intervention Types: Behavioral, Behavioral
Standard OEND
Behavioral
ActiveComparator Group · 1 Intervention: Standard OEND · Intervention Types: Behavioral

Trial Logistics

Trial Timeline

Screening: ~3 weeks
Treatment: Varies
Reporting: 12 months post-randomization

Who is running the clinical trial?

Brown UniversityLead Sponsor
409 Previous Clinical Trials
513,936 Total Patients Enrolled
2 Trials studying Drug Overdose
132 Patients Enrolled for Drug Overdose
National Institute on Drug Abuse (NIDA)NIH
2,228 Previous Clinical Trials
5,614,911 Total Patients Enrolled
16 Trials studying Drug Overdose
4,099 Patients Enrolled for Drug Overdose
Brandon DL Marshall, PhDPrincipal InvestigatorBrown University
2 Previous Clinical Trials
132 Total Patients Enrolled
2 Trials studying Drug Overdose
132 Patients Enrolled for Drug Overdose

Eligibility Criteria

Age 18+ · All Participants · 4 Total Inclusion Criteria

Mark “Yes” if the following statements are true for you:
You have used heroin, illicit stimulants, counterfeit prescription pills, or injection drugs in the past 30 days.

About The Reviewer

Michael Gill preview

Michael Gill - B. Sc.

First Published: October 3rd, 2021

Last Reviewed: November 30th, 2022

Michael Gill holds a Bachelors of Science in Integrated Science and Mathematics from McMaster University. During his degree he devoted considerable time modeling the pharmacodynamics of promising drug candidates. Since then, he has leveraged this knowledge of the investigational new drug ecosystem to help his father navigate clinical trials for multiple myeloma, an experience which prompted him to co-found Power Life Sciences: a company that helps patients access randomized controlled trials.