Physical Exercise for Disease

Phase-Based Estimates
1
Effectiveness
1
Safety
2500 Red Hill Avenue, Santa Ana, CA
Disease+2 More
Physical Exercise - Behavioral
Eligibility
< 18
All Sexes
Eligible conditions
Disease

Study Summary

This study is evaluating whether a physical exercise program may help reduce anxiety in children with autism.

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Eligible Conditions

  • Disease
  • Physical Exercise Condition
  • Control Condition

Treatment Effectiveness

Effectiveness Estimate

1 of 3

Compared to trials

Study Objectives

This trial is evaluating whether Physical Exercise will improve 1 primary outcome and 1 secondary outcome in patients with Disease. Measurement will happen over the course of Change from baseline at Week 8.

Week 8
Anxiety rating
Salivary Cortisol

Trial Safety

Safety Estimate

1 of 3

Compared to trials

Trial Design

2 Treatment Groups

Control Condition
Physical Exercise Condition

This trial requires 220 total participants across 2 different treatment groups

This trial involves 2 different treatments. Physical Exercise is the primary treatment being studied. Participants will all receive the same treatment. There is no placebo group. The treatments being tested are not being studied for commercial purposes.

Physical Exercise Condition
Behavioral
An eight week physical exercise intervention
Control Condition
Behavioral
An eight week control condition consisting of sedentary activities
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
Physical Exercise
2013
Completed Phase 4
~2170

Trial Logistics

Trial Timeline

Approximate Timeline
Screening: ~3 weeks
Treatment: Varies
Reporting: change from baseline at week 8
This trial has the following approximate timeline: 3 weeks for initial screening, variable treatment timelines, and roughly change from baseline at week 8 for reporting.

Who is running the study

Principal Investigator
J. G.
Prof. Jean Gehricke, Associate Professor
University of California, Irvine

Closest Location

2500 Red Hill Avenue - Santa Ana, CA

Eligibility Criteria

This trial is for patients born any sex aged 18 and younger. There are 5 eligibility criteria to participate in this trial as listed below.

Mark “yes” if the following statements are true for you:
This text is about children who are diagnosed with autism spectrum disorder (ASD) between the ages of 6 and 12 years old. show original
The person has a score that is in the 93rd percentile or above on the CBCL questionnaire or a total score of 25 or above on the SCARED questionnaire. show original
I am available to attend three times a week for eight consecutive weeks. show original
The ability to follow instructions is a skill that is important in many different settings show original
do not mutually exclusive Even though CalOptima Insurance or Medicaid does not allow for regular physical exercise, it is still possible to participate in moderate physical activity. show original

Patient Q&A Section

Please Note: These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

What causes disease?

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The origin of diabetes is not fully understood, but likely has a combination of causes including diet, genetics, and exposure to environmental threats. Cardiovascular disease and cancer are also both multifactorial: the main risk factors associated with both conditions are lifestyle factors including obesity, nutrition, and physical activity. The most common form of chronic disease is arthritis, which is likely to have a number of genetic and environmental factors involved. All of these conditions are commonly referred to as 'disease' because all have an underlying defect. Diabetes and cancer are of particular interest to researchers because they are two of the most common chronic diseases and have high morbidity and mortality rates. Understanding the cellular or molecular defects underlying disease is important for informing treatment and prevention.

Unverified Answer

How many people get disease a year in the United States?

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Approximately 200,000 deaths a year are directly attributed to diseases and injuries. The major limitation of the report is the current lack of accurate population-based statistics regarding diseases in the United States and their impact on mortality.

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Can disease be cured?

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Most current therapies have modest success rates. While new drug therapies are becoming more effective, many are still in development and have limited clinical utility. Current guidelines should focus on providing people the most effective interventions for relieving symptoms.

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What are the signs of disease?

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Signs of disease include bleeding of the gums, red nose, swollen and sore neck glands. Abdominal pain is common. There are a variety of common, but vague symptoms of disease, such as the common flu-like sensations. It is also possible for the first time onset symptoms (symptoms which could be a sign or symptom, but which do not necessarily have anything wrong) to be mistaken for a disease or sign itself, leading to delays in diagnosis and treatment.

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What are common treatments for disease?

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The treatment approach is highly dependent on the specific type of diseases and how advanced the disease is. Common options include lifestyle changes, exercise, medication, acupuncture, nutritional changes such as a healthy diet, and various other therapies.\n

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What is disease?

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The body consists of a network of organs and tissues that have a limited number of organs with specialized functions. It is the body's natural defense system that allows the human being to live to the age of adulthood and the ability to procreate and respond to the social environment. Once an individual begins to acquire a set of illnesses or disorders the body's natural defense system can no longer handle their symptoms and they may become diseased.

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What is physical exercise?

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The benefits of regular physical exercise on health-related quality of life are well documented. However, studies examining the impact of leisure-based exercise programmes on multiple health outcomes, including exercise capacity or physical functioning are lacking. Results from a recent clinical trial, we show that physical exercise is beneficial to exercise capacity and physical functioning in patients with moderate chronic obstructive pulmonary disease.

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Have there been other clinical trials involving physical exercise?

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This small pilot study indicates that it is feasible to find a clinical trial, albeit a small one, for a physical exercise intervention on the clinical outcomes of heart failure. Further investigation for exercise trials is necessary.

Unverified Answer

What are the common side effects of physical exercise?

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Participation in a physical exercise program was well tolerated. Muscle soreness after exercise was a common response among the population. We recommend that future investigations use a pain scoring system to assess the intensity of these reactions, which will then enable determination of the safest intensity to exercise.

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Is physical exercise typically used in combination with any other treatments?

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Physical exercise may be beneficial for patients with any type of cancer by reducing pain, promoting healing of the tumor and improving physical function in patients with any type of cancer. The clinical significance of these observations should be explored in future clinical trials.

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What is the latest research for disease?

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The research findings listed were from 2010 through 2014. Many of the newest findings should be recognized by nurses for their great impact on the field of oncognosy. To maximize the impact of the findings, nurses should collaborate with their fellows who share up-to-date knowledge.

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What is the primary cause of disease?

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If you have [cancer, autoimmune disease, cardiovascular disease, diabetes, or a neurological disease], there is a chance that the same will happen to you too. While the patient's doctor usually treats your condition, he/she must also be conscious of any possible side effects caused by possible drugs. As a result, many doctors check the medical records in order to find out more about the possible side effects. If you are looking to join a clinical trial, you can check out the power. withpower.com website. [power-health-research_withpower-withpower.

Unverified Answer
See if you qualify for this trial
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