30 Participants Needed

Exercise Timing for Type 2 Diabetes

Recruiting at 2 trial locations
SK
JK
Overseen ByJaclyn K Dosik
Age: 18+
Sex: Any
Trial Phase: Academic
Sponsor: Rutgers, The State University of New Jersey
Must be taking: Heart rate medications
No Placebo GroupAll trial participants will receive the active study treatment (no placebo)

What You Need to Know Before You Apply

What is the purpose of this trial?

The overall purpose of the study is to test the effect of Noom on exercise and diet advice in adults with type 2 diabetes. The overarching hypothesis is that the use of Noom may promote better dietary adherence during an exercise program, thereby promoting greater weight loss and cardiometabolic health compared to lifestyle advice only. In particular, the investigators anticipate that changes in metabolic and vascular insulin sensitivity will correlate with glycemic control and blood pressure changes.

Do I have to stop taking my current medications for the trial?

The trial does not specify if you need to stop taking your current medications. However, if you are taking active weight suppression medication, you cannot participate in the trial.

What safety data exists for exercise timing in type 2 diabetes treatment?

The provided research does not directly address safety data for exercise timing in type 2 diabetes treatment. However, it suggests that exercise, whether in the morning or afternoon, can have beneficial effects on metabolic health, insulin sensitivity, and glycemic control. No specific safety concerns are mentioned, indicating that exercise timing is generally safe for individuals with type 2 diabetes, but the optimal timing for maximum benefit may vary.12345

Is the treatment 'Exercise Afternoon, Exercise and nutrition, Exercise Morning, Noom mobile application' promising for type 2 diabetes?

Yes, exercising in the afternoon seems to be a promising treatment for type 2 diabetes. It can improve insulin sensitivity, lower blood sugar levels, and reduce body fat more effectively than morning exercise. Combining exercise with nutrition advice or using tools like the Noom app can further support these benefits.12367

What data supports the idea that Exercise Timing for Type 2 Diabetes is an effective treatment?

The available research shows that exercising at specific times can help manage blood sugar levels in people with Type 2 Diabetes. For example, one study found that moderate exercise after dinner can improve blood sugar control. Another study suggests that timing exercise to target high blood sugar levels after meals might help improve overall heart and blood sugar health. These findings indicate that when you exercise can be just as important as how much you exercise for managing Type 2 Diabetes.1891011

Who Is on the Research Team?

SK

Steven K Malin, PhD

Principal Investigator

Rutgers University - New Brunswick

Are You a Good Fit for This Trial?

Adults aged 30-70 with type 2 diabetes, a BMI between 28 and 45, not currently on weight loss meds or insulin therapy. Mustn't have significant heart, liver, kidney diseases or cancer. Non-smokers only (or those who quit over a year ago), not pregnant/nursing, and haven't been exercising regularly.

Inclusion Criteria

I am currently on medication that affects my heart rate or rhythm.
I am between 30 and 70 years old.
I have been diagnosed with type 2 diabetes.
See 1 more

Exclusion Criteria

I have type 1 diabetes and need insulin.
You are allergic to perflutren, which is in the study drug Definity.
My BMI is either above 46 or below 27.
See 10 more

Timeline for a Trial Participant

Screening

Participants are screened for eligibility to participate in the trial

2-4 weeks

Treatment

Participants engage in exercise training either in the morning or afternoon for 2 weeks, supervised and at moderate to hard intensity

2 weeks

Follow-up

Participants are monitored for changes in body weight, glucose tolerance, and flow-mediated dilation

4 weeks

What Are the Treatments Tested in This Trial?

Interventions

  • Exercise Afternoon
  • Exercise and nutrition
  • Exercise Morning
  • Noom mobile application
Trial Overview The trial is testing the effectiveness of Noom for improving diet adherence during exercise in the morning vs. afternoon for better weight loss and heart health in type 2 diabetics. It's checking if this leads to better blood sugar control and blood pressure.
How Is the Trial Designed?
2Treatment groups
Experimental Treatment
Active Control
Group I: Morning ExerciseExperimental Treatment1 Intervention
Group II: Afternoon ExerciseActive Control1 Intervention

Find a Clinic Near You

Who Is Running the Clinical Trial?

Rutgers, The State University of New Jersey

Lead Sponsor

Trials
471
Recruited
81,700+

Noom Inc.

Industry Sponsor

Trials
17
Recruited
2,800+

Published Research Related to This Trial

In a study involving 15 inactive patients with type 2 diabetes, moderate exercise 60 minutes after dinner was found to significantly lower 2-hour postprandial glucose levels compared to exercising 30 minutes after dinner.
Both exercise timings were safe, with no incidents of nocturnal hypoglycemia reported, suggesting that while 60 minutes post-dinner may be more effective for glycemic control, 30 minutes post-dinner could be a safer option for those at risk of low blood sugar.
[Effect of moderate exercise for 30 min at 30 min versus 60 min after dinner on glycemic control in patients with type 2 diabetes: a randomized, crossover, self-controlled study].Li, Z., Hu, Y., Ma, J.[2022]
In a study involving 50 overweight women, exercising in the morning resulted in significantly higher levels of satiety compared to exercising in the afternoon, suggesting that morning workouts may help control hunger better.
Overall, the timing of moderate-intensity exercise did not significantly affect appetite or energy intake patterns over the following 24 hours, indicating that the benefits of exercise on weight management may not depend on when it is performed.
Acute Effect of Morning and Afternoon Aerobic Exercise on Appetite of Overweight Women.Alizadeh, Z., Mostafaee, M., Mazaheri, R., et al.[2020]
A randomized controlled trial involving 70 individuals with type 2 diabetes will investigate whether exercising at the time of peak blood sugar levels can improve glycaemic control, specifically by measuring changes in HbA1c over a 5-month period.
The study will also assess secondary outcomes related to cardiovascular health, such as vascular function and body composition, to determine the broader benefits of timing exercise for individuals with type 2 diabetes.
Personalising activity to target peak hyperglycaemia and improve cardiometabolic health in people with type 2 diabetes: protocol for a randomised controlled trial.Chang, CR., Astell-Burt, T., Russell, BM., et al.[2022]

Citations

[Effect of moderate exercise for 30 min at 30 min versus 60 min after dinner on glycemic control in patients with type 2 diabetes: a randomized, crossover, self-controlled study]. [2022]
Acute Effect of Morning and Afternoon Aerobic Exercise on Appetite of Overweight Women. [2020]
Personalising activity to target peak hyperglycaemia and improve cardiometabolic health in people with type 2 diabetes: protocol for a randomised controlled trial. [2022]
A randomized, controlled trial to study the effect of exercise consultation on the promotion of physical activity in people with Type 2 diabetes: a pilot study. [2022]
Impact of post-meal and one-time daily exercise in patient with type 2 diabetes mellitus: a randomized crossover study. [2020]
Exercise training elicits superior metabolic effects when performed in the afternoon compared to morning in metabolically compromised humans. [2021]
Chronobiology of exercise: the influence of scheduling upon glycemic responses of control and of subjects with diabetes mellitus. [2011]
Examining the Role of Exercise Timing in Weight Management: A Review. [2022]
The role of physical activity in the control of obesity. [2021]
10.United Statespubmed.ncbi.nlm.nih.gov
Exercise recommendations for patients with type 2 diabetes. [2017]
11.United Statespubmed.ncbi.nlm.nih.gov
Exercise Timing in Type 2 Diabetes Mellitus: A Systematic Review. [2019]
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