Treatment for Diabetes Mellitus

Phase-Based Estimates
1
Effectiveness
1
Safety
Albert Einstein College Of Medicine/Montefiore MC, Bronx, NY
Diabetes Mellitus+2 More
Eligibility
18+
Female
Eligible conditions
Diabetes Mellitus

Study Summary

This study is evaluating whether a mobile health app can improve clinical outcomes for people with asthma and diabetes.

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Eligible Conditions

  • Diabetes Mellitus
  • Asthma
  • Mobile Health

Treatment Effectiveness

Effectiveness Estimate

1 of 3

Study Objectives

This trial is evaluating whether Treatment will improve 2 primary outcomes and 8 secondary outcomes in patients with Diabetes Mellitus. Measurement will happen over the course of 3 months.

3 months
Asthma and/or diabetes related emergency department visits and hospitalizations
Asthma control measured by the Asthma Control Test.
Asthma quality of life measured by the Mini-Asthma Quality of Life Questionnaire.
Diabetes Empowerment Scale-Short Form
Diabetes quality of life measured by the Diabetes Quality of Life instrument
Diabetes self-management and self-efficacy as measured by the Diabetes Self-Management Questionnaire
Patient Health Questionnaire-9 for depression
Patient usage of WELLXcel from the backend administrative panel.
Unified Theory of Acceptance and Use of Technology questionnaire
patient satisfaction regarding the WELLXcel intervention measured by the validated Questionnaire for User Interface Satisfaction (QUIS)

Trial Safety

Safety Estimate

1 of 3

Trial Design

2 Treatment Groups

HIV +

This trial requires 60 total participants across 2 different treatment groups

This trial involves 2 different treatments. Treatment is the primary treatment being studied. Participants will all receive the same treatment. There is no placebo group. The treatments being tested are not being studied for commercial purposes.

HIV +
Behavioral
Patients will have the application and use it to increase their awareness about their medical condition.
HIV -
Behavioral
Patients will have the application and use it to increase their awareness about their medical condition.

Trial Logistics

Trial Timeline

Approximate Timeline
Screening: ~3 weeks
Treatment: Varies
Reporting: 3 months
This trial has the following approximate timeline: 3 weeks for initial screening, variable treatment timelines, and roughly 3 months for reporting.

Who is running the study

Principal Investigator
S. P. J.
Sunit P. Jariwala, Associate Profesor
Montefiore Medical Center

Closest Location

Albert Einstein College Of Medicine/Montefiore MC - Bronx, NY

Eligibility Criteria

This trial is for female patients aged 18 and older. There are 3 eligibility criteria to participate in this trial as listed below.

Mark “yes” if the following statements are true for you:
People who have asthma (diagnosis via self-report) on a daily controller medication and/or Type 2 diabetes mellitus (diagnosis via self-report) on at least one oral hypoglycemic medication and/or Insulin are considered to have persistent illness. show original
able to understand the information given. show original
You can access your Smartphone (iOS or Android) from any computer that has an internet connection. show original

Patient Q&A Section

Please Note: These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Can diabetes mellitus be cured?

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Diabetic patients have high levels of microalbuminuria and high levels of HbA1c. If diabetic patients get their HbA1c to 5.0 percent, then many people in this subgroup with microalbuminuria and low levels of folic acid might be improved significantly as evidenced by improved renal and cardiovascular outcomes.

Unverified Answer

What causes diabetes mellitus?

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Diabetes can be linked to a number of genetic, physiological, dietary and environmental factors. The development of diabetes is usually a gradual process, with different mechanisms working together. Diabetes has been shown to increase the risk of cancer. Diabetes is a risk factor for coronary heart disease. Smoking, obesity and lack of exercise are risk factors for cardiovascular disease. A higher rate of postmenopausal hormone replacement use increases one's risk of osteoporotic fractures.

Unverified Answer

What are common treatments for diabetes mellitus?

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Oral hypoglycemic agents (e.g., metformin, buformin, or glibenclamide), insulin/insulin analogs (e.g., NPH, human insulin), and metformin combined with insulin/insulin analogs constitute the current, preferred, standards of care for treatment of the majority of patients with diabetes.

Unverified Answer

How many people get diabetes mellitus a year in the United States?

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Diabetes accounts for 10% of all Medicare payments in the Unites States, totaling over $17 Billion annually. The number of people who suffer from diabetes-related complications is growing, thus increasing the healthcare expenditure.

Unverified Answer

What is diabetes mellitus?

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Approximately 24% of the U.S. population has diabetes, which has a major impact on many life domains. Many people with diabetes lack full knowledge of this serious condition and the options for control and well-being.

Unverified Answer

What are the signs of diabetes mellitus?

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Early signs of diabetes include loss of appetite, tiredness and sweating. The next and most notable signs of diabetes are fatigue, increased thirst, blurry or double vision, frequent urination, abnormal urine colour, and leg swelling.

Unverified Answer

What are the latest developments in treatment for therapeutic use?

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Since the advent of insulin, clinicians and researchers have used different forms of insulin in clinical trials. This is important because each therapy has its own unique efficacy and side effects. There are also limitations when deciding treatment for patients, in particular if a disease with a good potential for cure is being considered. Recent pharmacological advances enable us to develop better-tolerated and more efficacious drugs.

Unverified Answer

Have there been any new discoveries for treating diabetes mellitus?

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Diabetes treatment is very effective, although the long-term effects of diabetes control are hard to define. There have been important discoveries (as reported below) in the field of diabetes research; however, it is still not possible to completely eradicate the disease.

Unverified Answer

What is the average age someone gets diabetes mellitus?

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Type 1 Diabetes Incidence increases faster with age, making it a key part of the national public health strategy. Diabetes is a major cause of morbidity and mortality in the United States. The CDC estimates that 2% of adults aged 20 and above will develop [type 1 diabetes](https://www.withpower.com/clinical-trials/type-1-diabetes) in their lifetimes. The population of this study is fairly representative as it does not include populations of younger ages, and it contains all races and ethnic groups to make it a very broad sample of the population. Recent findings found by this study were used to create a population-based model. This model may be used as part of educational tools to aid health care providers and the public in the prevention and treatment of type 1 diabetes.

Unverified Answer

Is treatment safe for people?

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A treatment programme led by a specialist diabetes specialist, incorporating multidisciplinary input, is effective in changing glucose homeostasis and has no evidence of any long-term adverse effects. We recommend that a treatment programme incorporating multidisciplinary input to reduce hyperglycaemia be explored in practice.

Unverified Answer

How does treatment work?

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The current consensus suggests that type 1 diabetes is probably due to a T cell dependent autoimmune process. The autoimmune process results in autoantibodies that target cells as well as their normal cellular counterparts. It is not clear whether these antibodies can cross the blood-brain barrier into the brain and destroy its own cells or whether they target the cells of the brain. This treatment targets the immune system, which is the mechanism that the body employs to fight infection and to protect itself from disease. If type 1 diabetes treatment works, it could be used to treat other autoimmune diseases. Current and potential therapeutic approaches for type 1 diabetes treatment are discussed.

Unverified Answer

How serious can diabetes mellitus be?

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[There is no significant morbidity or mortality advantage in treating diabetes mellitus in individuals without comorbidities] The current level of care for diabetic endocarditis may be insufficient in most jurisdictions. Improved access to endocarditis prophylaxis may prevent a significant amount of morbidity and death in high/mortality-risk individuals.

Unverified Answer
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