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Ketone Supplement

D-β-hydroxybutyric acid with R-1,3-butanediol for High Blood Sugar

N/A
Waitlist Available
Led By Jonathan Little, PhD
Research Sponsored by University of British Columbia
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up start of enrolment to completion of enrolment
Awards & highlights

Study Summary

This trial will investigate whether drinking ketone supplements can help improve blood sugar control and influence how cells function in people with type 2 diabetes.

Eligible Conditions
  • Diabetes
  • High Blood Sugar
  • Ketosis

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~days -5 through 9 (5 days of baseline and first 9 days of intervention period) and days 77 through 90 (last 2 weeks)
This trial's timeline: 3 weeks for screening, Varies for treatment, and days -5 through 9 (5 days of baseline and first 9 days of intervention period) and days 77 through 90 (last 2 weeks) for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
To determine the feasibility of conducting a randomized controlled trial (RCT) on the effects of consumption of a ketone supplement in adults with type 2 diabetes in free-living environment for 90 days: Recruitment rate of participants into the trial
To determine the feasibility of conducting such an RCT: Compliance as measured by the self-reported volume of ketone supplement drink consumed
To determine the feasibility of conducting such an RCT: Retention as measured by the number of participants that complete the study
Secondary outcome measures
Cravings
Gastrointestinal distress
Hematology panel
+17 more
Other outcome measures
Intervention acceptability
Viability of methods

Trial Design

2Treatment groups
Experimental Treatment
Placebo Group
Group I: Exogenous Ketone SupplementExperimental Treatment1 Intervention
Participants will be instructed to consume a total of 711 mL of the exogenous ketone supplement drink (for a total of 30 g of beta-hydroxybutyrate) per day (3 doses at 237 mL containing 10 g of beta-hydroxybutyrate each) for a period of 90 days.
Group II: Inert placeboPlacebo Group1 Intervention
Participants will be instructed to consume an equivalent volume (711 mL) of taste- and volume-matched placebo per day (3 doses at 237 mL) for 90 days.

Find a Location

Who is running the clinical trial?

University of British ColumbiaLead Sponsor
1,415 Previous Clinical Trials
2,466,996 Total Patients Enrolled
Jonathan Little, PhDPrincipal InvestigatorUniversity of British Columbia
3 Previous Clinical Trials
185 Total Patients Enrolled

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Am I a qualified candidate for enrollment in this experiment?

"This trial has room for 36 participants aged between 30 and 69 who have ketosis. Furthermore, they must possess a physician-confirmed diagnosis of type 2 diabetes that is at least 1 year old, be taking glucose medications consistently for the past 3 months, and comprehend English well enough to complete study questionnaires."

Answered by AI

What is the desired outcome of this clinical experiment?

"The 90-day study will evaluate the efficiency of recruiting patients for a randomized control trial on ketone supplement usage in adults with type 2 diabetes. Alongside this primary objective, cravings, self-rated health and blood pressure (systolic/diastolic) will be assessed via questionnaires and monitors respectively."

Answered by AI

What is the current enrollment figure for this clinical investigation?

"Affirmative. According to the information on clinicaltrials.gov, this medical investigation is still searching for volunteers who meet their inclusion criteria. The trial was unveiled on September 28th 2022 and its most recent update occurred November 1st of that same year. 36 participants are needed from a single location."

Answered by AI

Is the possibility of enrolling in this trial currently available for individuals?

"Indeed, the data available on clinicaltrials.gov confirms that this medical study is actively enlisting participants. First posted on September 28th 2022 and last edited November 1st 2022, 36 patients are needed from a single location to take part in the trial."

Answered by AI

Is this experiment open to those over the age of eighty-five?

"This clinical trial is limited to those aged 30 and above, up to the upper age limit of 69 years."

Answered by AI
Recent research and studies
clinicaltrials.govStudy
Examining the Feasibility of Prolonged Ketone Supplement Drink Consumption in Adults With Type 2 Diabetes
Jonathan Little 2022. "Examining the Feasibility of Prolonged Ketone Supplement Drink Consumption in Adults With Type 2 Diabetes". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT05477368.
~8 spots leftby Apr 2025
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