Band Together for Psychosis, Involutional

Phase-Based Estimates
1
Effectiveness
1
Safety
University of Washington Department of Psychiatry and Behavioral Sciences, Seattle, WA
Psychosis, Involutional+1 More
Band Together - Behavioral
Eligibility
18+
All Sexes
Eligible conditions
Psychosis, Involutional

Study Summary

This study is evaluating whether a video game may help improve cognitive control and mood in older adults.

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Eligible Conditions

  • Psychosis, Involutional
  • Depressive Disorder, Major
  • Major Depressive Disorder (MDD)

Treatment Effectiveness

Effectiveness Estimate

1 of 3

Study Objectives

This trial is evaluating whether Band Together will improve 3 primary outcomes in patients with Psychosis, Involutional. Measurement will happen over the course of 8 weeks.

8 weeks
CCN Function (Circuitry and Performance)
CCN Function (Self-Report- Depressive Symptoms)
CCN Function (Self-Report- Disability)

Trial Safety

Safety Estimate

1 of 3

Trial Design

2 Treatment Groups

Control Arm (R 33)
Intervention Arm (R 33)
Placebo group

This trial requires 79 total participants across 2 different treatment groups

This trial involves 2 different treatments. Band Together is the primary treatment being studied. Participants will all receive the same treatment. Some patients will receive a placebo treatment. The treatments being tested are not being studied for commercial purposes.

Intervention Arm (R 33)
Behavioral
a mobile 3D video game (Band Together) that has been shown to reduce older adults' susceptibility to interference by augmenting sustained attention and working memory abilities (e.g. cognitive control) through targeted adaptive algorithms.
Control Arm (R 33)
Other
a mobile 3D video game to be used as placebo.
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
Band Together
2015
N/A
~20

Trial Logistics

Trial Timeline

Approximate Timeline
Screening: ~3 weeks
Treatment: Varies
Reporting: 8 weeks
This trial has the following approximate timeline: 3 weeks for initial screening, variable treatment timelines, and roughly 8 weeks for reporting.

Who is running the study

Principal Investigator
P. A.
Prof. Pat Arean, Professor, Psychiatry and Behavioral Sciences
University of Washington

Closest Location

University of Washington Department of Psychiatry and Behavioral Sciences - Seattle, WA

Eligibility Criteria

This trial is for patients born any sex aged 18 and older. There is one eligibility criterion to participate in this trial as listed below.

Mark “yes” if the following statements are true for you:
(1) Age 45 to 75; (2) unipolar, nonpsychotic major depression (by SCID, DSM-V), (3) Hamilton Depression Rating Scale > 20; (4) off antidepressants or have been on a stable dose for 12 weeks and do not intend to change dose in the next 5 weeks, (5) capacity to consent; (6) ability to participate in MRI.

Patient Q&A Section

Please Note: These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Can psychosis, involutional be cured?

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Involuntary commitments are an integral part of mental health rehabilitation because, although psychosis, involutional, and other mental states are largely untreatable, a substantial proportion of people in involutional mental health facilities will experience some degree of improvement, possibly with intensive intervention.

Unverified Answer

What are common treatments for psychosis, involutional?

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Patients can present with depressive or psychotic symptoms. Treatment is similar to any mental health issues. It is crucial to discuss medication with the client and to monitor for side effects.

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What are the signs of psychosis, involutional?

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We suggest that the signs of psychosis, involutional, are very similar to those found in the elderly, and therefore both may be seen in a similar group of patients, and should not be treated differently.

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How many people get psychosis, involutional a year in the United States?

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Approximately 2 million are diagnosed with psychosis on a yearly basis. The most common causes are mental disorders, particularly schizophrenia and mania. Approximately half the cases are of an acute onset, and the remainder are mostly of a chronic, insidious, and unremitting type.

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What is psychosis, involutional?

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It has been reported that it was first introduced into the neurology literature by the psychiatrist Emil Kraepelin in 1924. In the medical science literature, psychosis is still referred to as a neuropsychiatric, or neuro-psychiatric disorder, as well as neurotic psychosis. The word implies a breakdown of thought that is generally undesirable in society and can result in, a lack of, or changes in, thinking and behavior. Schizophrenia is a neuropsychiatric disorder that affects some people, causing them to have mood swings and a diminished capacity to distinguish reality from dream, hallucination, delusions and other distortions of thought. If people do not receive treatment they may not recover.

Unverified Answer

What causes psychosis, involutional?

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Involution is a frequent occurrence, in all age groups. The causes are unknown, although the age distribution of schizophrenia cases indicates that they are genetically determined, and are probably only a subset of a genetically polygenic illness. The causes of other age related psychiatric diseases and disorders are also unknown.

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What is the average age someone gets psychosis, involutional?

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The median age for psychosis in our population was 67 years; 74% of patients had an incident of psychosis. About 2% of patients with psychosis developed dementia. The median age of dementing patients was 75 years.

Unverified Answer

Has band together proven to be more effective than a placebo?

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Band together showed no beneficial effect on depression or global outcomes when compared to banded not banded. Banded did not differ from banded placebo. Banded did not increase remission of depression. Banded did not change physical functioning nor did it improve subjective well-being or quality of life. Banded did not improve social function, and did not change self-reported depression, global or physical functioning, and quality of life. Banded did not improve satisfaction of care. Banded did not improve adherence to medication. Banded did not change levels of medication side effects. Banded did not change the number of side effects. Banded did not change levels of medication side effects. Banded did not change satisfaction with care in depressed patients.

Unverified Answer

What is band together?

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Results from a recent clinical trial demonstrate that psychotic patients can be successfully integrated into community-based rehabilitation. Their functioning can be improved by a brief, intensive intervention tailored to patients' needs involving psychosocial interventions, skills training and group support.

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How does band together work?

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In a recent study, findings of this study support the use of BND in treatment of PD. The BND is an inexpensive, highly effective, well-tolerated and safe mode of treating patients with PD.

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Does band together improve quality of life for those with psychosis, involutional?

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This pilot study showed that the QoL measures used in this study are sensitive to QoL change in people with psychosis, who are treated by a multi-disciplinary team. However, further research is required to determine the best ways to assess and report change, and to further evaluate why people in the bands tended to have higher QoL scores pre-intervention.

Unverified Answer

Is band together safe for people?

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A band is a valid treatment approach for the majority of young children with the symptoms of a panic disorder, anxiety, or other anxiety disorder. The use of behavioral approaches in addition to medical treatment may improve both outcomes and cost, especially in cases that would be considered 'ineligible' on the basis of medical criteria.

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