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Experimental for Depression

N/A
Waitlist Available
Led By Diego A Pizzagalli, PhD
Research Sponsored by Mclean Hospital
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be between 18 and 65 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up through study completion (approximately at hour 4 of study)
Awards & highlights

Study Summary

This study is evaluating whether biogenetic feedback may have an impact on motivation for different psychiatric treatment modalities.

Eligible Conditions
  • Depression

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~through study completion (approximately at hour 4 of study)
This trial's timeline: 3 weeks for screening, Varies for treatment, and through study completion (approximately at hour 4 of study) for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Default Mode Network Connectivity
Error Positivity (Pe)
Secondary outcome measures
Treatment Credibility and Expectancy Questionnaire

Trial Design

2Treatment groups
Experimental Treatment
Active Control
Group I: ExperimentalExperimental Treatment1 Intervention
This group of participants will receive the feedback that they have a genetic vulnerability to depression.
Group II: ControlActive Control1 Intervention
This group of participants will receive the feedback that they do not have a genetic vulnerability to depression.

Find a Location

Who is running the clinical trial?

Mclean HospitalLead Sponsor
213 Previous Clinical Trials
21,614 Total Patients Enrolled
46 Trials studying Depression
3,531 Patients Enrolled for Depression
Diego A Pizzagalli, PhDPrincipal InvestigatorMclean Hospital
4 Previous Clinical Trials
491 Total Patients Enrolled
2 Trials studying Depression
237 Patients Enrolled for Depression

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.
Recent research and studies
Behaviour Research and TherapyJournal
Development and Validation of the Penn State Worry Questionnaire
Meyer, T.J., M.L. Miller, R.L. Metzger, and Thomas D. Borkovec. 1990. “Development and Validation of the Penn State Worry Questionnaire”. Behaviour Research and Therapy. Elsevier BV. doi:10.1016/0005-7967(90)90135-6.
L'EncéphaleJournal
Étude préliminaire comparative de l’instrument d’évaluation des troubles de la personnalité DIP avec l’entretien semi-structuré SCID-II
Massoubre, C., H. Bonnefond, A. Grosselin, A. Nelva, J. Pellet, and F. Lang. 2009. “Étude préliminaire comparative de l’instrument d’évaluation des troubles de la personnalité DIP avec l’entretien semi-structuré SCID-II”. L'encéphale. Elsevier BV. doi:10.1016/j.encep.2008.09.007.
Trends in Cognitive SciencesJournal
The Variable Nature of Cognitive Control: A Dual Mechanisms Framework
Braver, Todd S.. 2012. “The Variable Nature of Cognitive Control: A Dual Mechanisms Framework”. Trends in Cognitive Sciences. Elsevier BV. doi:10.1016/j.tics.2011.12.010.
Journal of Abnormal PsychologyJournal
Tripartite Model of Anxiety and Depression: Psychometric Evidence and Taxonomic Implications.
Clark, Lee Anna, and David Watson. 1991. “Tripartite Model of Anxiety and Depression: Psychometric Evidence and Taxonomic Implications.”. Journal of Abnormal Psychology. American Psychological Association (APA). doi:10.1037/0021-843x.100.3.316.
~15 spots leftby Apr 2025
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