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Device

Active rTMS for Depression

N/A
Waitlist Available
Led By Jonathan Downar
Research Sponsored by University Health Network, Toronto
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up baseline (week prior to treatment) and after 1 week and 4 weeks post-treatment
Awards & highlights

Study Summary

This trial will test if additional sessions of transcranial magnetic stimulation can help people with major depression achieve remission.

Eligible Conditions
  • Depression

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~baseline (week prior to treatment) and after 1 week and 4 weeks post-treatment
This trial's timeline: 3 weeks for screening, Varies for treatment, and baseline (week prior to treatment) and after 1 week and 4 weeks post-treatment for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Beck Depression Inventory-II (BDI-II) (score 0-63, higher = more severe)
Secondary outcome measures
Hamilton Depression Rating Scale 17-items (HDRS17) (score 0-52, higher = more severe)

Trial Design

1Treatment groups
Experimental Treatment
Group I: Active rTMSExperimental Treatment1 Intervention
Treatment will be delivered daily (weekdays) rTMS treatments, for up to 10 daily sessions and up to 75 sessions in total.
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
Repetitive Transcranial Magnetic Stimulation (rTMS)
2019
Completed Phase 2
~780

Find a Location

Who is running the clinical trial?

University Health Network, TorontoLead Sponsor
1,476 Previous Clinical Trials
485,130 Total Patients Enrolled
53 Trials studying Depression
12,100 Patients Enrolled for Depression
Centre for Addiction and Mental HealthOTHER
356 Previous Clinical Trials
81,408 Total Patients Enrolled
85 Trials studying Depression
19,201 Patients Enrolled for Depression
Jonathan DownarPrincipal InvestigatorUniversity Health Network, Toronto

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.
Recent research and studies
clinicaltrials.govStudy
Repetitive Transcranial Magnetic Stimulation Trajectory of Outcomes Study
Jonathan Downar 2019. "Repetitive Transcranial Magnetic Stimulation Trajectory of Outcomes Study". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT04376697.
All > Transcranial Magnetic Stimulation
~8 spots leftby May 2025
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