Behavioral Activation (BA) Therapy for Teen Depression

Phase-Based Progress Estimates
Teen Depression+1 MoreBehavioral Activation (BA) Therapy - Behavioral
12 - 15
All Sexes
What conditions do you have?

Study Summary

This trial is testing whether two different interventions for depression, Behavioral Activation (BA) and Problem Solving Therapy (PST), are more or less effective depending on a person's exposure to adverse childhood experiences.

Eligible Conditions
  • Adverse Childhood Experiences
  • Teen Depression

Treatment Effectiveness

Study Objectives

7 Primary · 2 Secondary · Reporting Duration: Pre-intervention vs. 1-month post-intervention

Immediately post-intervention
Executive functioning (planning initial thinking time)
Executive functioning (planning moves)
Executive functioning (planning total)
Executive functioning (task-switching congruent errors)
Executive functioning (task-switching incongruent errors)
Executive functioning (task-switching reaction latency)
Executive functioning (task-switching total incorrect)
Reward responsiveness immediately post-intervention
Reward sensitivity immediately post-intervention
Pre-intervention vs. 1-month post-intervention
Change in clinician-rated depression symptoms from baseline to one-month follow-up
Change in self-reported depression symptoms from baseline to one-month follow-up
immediately post-intervention; baseline vs. 1-month follow-up
Problem Resolution Outcome Survey (PROS) up to 1-month follow-up
immediately post-intervention; baseline vs. 1-month post-intervention
Behavioral Activation for Depression Scale (BADS) up to 1-month follow-up
Reward Probability Index (RPI) up to 1-month follow-up

Trial Safety

Trial Design

2 Treatment Groups

Problem Solving Therapy (PST)
1 of 2
Behavioral Activation (BA) Therapy
1 of 2

Active Control

Experimental Treatment

40 Total Participants · 2 Treatment Groups

Primary Treatment: Behavioral Activation (BA) Therapy · No Placebo Group · N/A

Behavioral Activation (BA) Therapy
Experimental Group · 1 Intervention: Behavioral Activation (BA) Therapy · Intervention Types: Behavioral
Problem Solving Therapy (PST)
ActiveComparator Group · 1 Intervention: Problem Solving Therapy (PST) · Intervention Types: Behavioral

Trial Logistics

Trial Timeline

Screening: ~3 weeks
Treatment: Varies
Reporting: pre-intervention vs. 1-month post-intervention

Who is running the clinical trial?

University of PittsburghLead Sponsor
1,617 Previous Clinical Trials
16,298,455 Total Patients Enrolled
The Klingenstein Third Generation FoundationOTHER
4 Previous Clinical Trials
1,311 Total Patients Enrolled
Rachel A Vaughn-Coaxum, Ph.D.Principal InvestigatorUniversity of Pittsburgh
1 Previous Clinical Trials
90 Total Patients Enrolled

Eligibility Criteria

Age 12 - 15 · All Participants · 2 Total Inclusion Criteria

Mark “Yes” if the following statements are true for you:
You have elevated depressive symptoms.