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Behavioural Intervention

CBT vs Mindfulness-Based Therapy for Autism

N/A

Recruiting

Led By Brenna Maddox, PhD

Research Sponsored by University of North Carolina, Chapel Hill

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

≥18 years of age

Co-occurring depression and/or anxiety as determined by a score ≥10 on the PHQ-ADS depression and/or anxiety subscale

Timeline

Screening 3 weeks

Treatment Varies

Follow Up up to 6-months follow-up

Awards & highlights

Study Summary

This trial will compare CBT & MBT, two treatments for depression & anxiety in autistic adults, to see which is more effective.

Who is the study for?

This trial is for English-speaking autistic adults over 18 living in North Carolina or Virginia. Participants must have a professional autism diagnosis or score high on an autism screening, and show signs of depression or anxiety. Those with acute mental issues, intoxication, mania, or at risk of suicide cannot join.Check my eligibility

What is being tested?

The study compares Cognitive-Behavioral Therapy (CBT) and Mindfulness-Based Cognitive Therapy (MBCT) to see which is more effective for treating depression and anxiety in autistic adults. Both therapies will be given through telehealth sessions.See study design

What are the potential side effects?

While CBT and MBCT are generally safe, some may experience increased anxiety, emotional discomfort during sessions, fatigue after therapy work, or frustration if expected improvements aren't seen.

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below

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I am 18 years old or older.

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I have depression or anxiety with a score of 10 or more on the PHQ-ADS.

Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ up to 6-months follow-up

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~up to 6-months follow-up

This trial's timeline: 3 weeks for screening, Varies for treatment, and up to 6-months follow-up for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.

Primary outcome measures

Change in anxiety and depression symptoms

Secondary outcome measures

Change in disability

Change in functional impairment

Change in mental health

+7 more

Trial Design

2Treatment groups

Active Control

Group I: Cognitive-Behavioral Therapy (CBT)Active Control1 Intervention

The arm receives the Unified Protocol (UP), a modular transdiagnostic CBT treatment that uses a parsimonious approach to treatment by addressing common emotion-related mechanisms underlying both anxiety and depression.

Group II: Mindfulness-Based Cognitive Therapy (MBCT)Active Control1 Intervention

Mindfulness-Based Cognitive Therapy (MBCT) is an empirically supported treatment that focuses on non-judgmental acceptance of present moment experiences and emotions. MBCT was adapted from Mindfulness-Based Stress Reduction (MBSR) to focus on improving mental health more specifically in individuals with depression and other psychiatric conditions.

0 / 2Eligibility criteria met

Find a Location

Who is running the clinical trial?

University of North Carolina, Chapel HillLead Sponsor

1,508 Previous Clinical Trials

4,190,742 Total Patients Enrolled

Patient-Centered Outcomes Research InstituteOTHER

551 Previous Clinical Trials

29,997,158 Total Patients Enrolled

University of VirginiaOTHER

754 Previous Clinical Trials

1,244,773 Total Patients Enrolled

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Is enrollment for this experiment still available?

"The details recorded on clinicaltrials.gov indicate that this trial, which went online October 15th 2023 and was last updated September 22nd 2023, is no longer accepting new participants. Fortunately, 1716 other research studies are currently recruiting patients at present."

Answered by AI