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Behavioral testing for Depression

N/A
Waitlist Available
Research Sponsored by Brigham and Women's Hospital
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up 1 year after study completion
Awards & highlights

Study Summary

This trial will test whether transcranial magnetic stimulation (TMS) to the left dorsal lateral prefrontal cortex (DLPFC) can help subjects with medication-refractory depression. 100 subjects will be recruited and undergo TMS treatment, questionnaires, and a behavioral testing battery. MRI data will be used to identify brain regions whose connectivity to the stimulation site co-varies with the improvement of symptoms.

Eligible Conditions
  • Depression

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~1 year after study completion
This trial's timeline: 3 weeks for screening, Varies for treatment, and 1 year after study completion for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Prediction of intermittent theta burst stimulation (iTBS) clinical response
Prediction of repetitive Transcranial Magnetic Stimulation (rTMS) clinical response

Trial Design

1Treatment groups
Experimental Treatment
Group I: MRI and behavioral assessment for patients receiving TMSExperimental Treatment2 Interventions
Subjects will undergo an hour-long MRI scanning session, a marking for the site of planned clinical TMS stimulation and a behavioral testing battery before and after their TMS treatment course.

Find a Location

Who is running the clinical trial?

Brigham and Women's HospitalLead Sponsor
1,615 Previous Clinical Trials
11,470,770 Total Patients Enrolled
28 Trials studying Depression
115,893 Patients Enrolled for Depression
Butler HospitalOTHER
129 Previous Clinical Trials
16,358 Total Patients Enrolled
31 Trials studying Depression
6,329 Patients Enrolled for Depression
Massachusetts General HospitalOTHER
2,933 Previous Clinical Trials
13,198,421 Total Patients Enrolled
184 Trials studying Depression
29,496 Patients Enrolled for Depression

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Who else is applying?

What state do they live in?
New York
Massachusetts
How old are they?
18 - 65
What site did they apply to?
Brigham and Women's Hospital
What portion of applicants met pre-screening criteria?
Met criteria
Recent research and studies
clinicaltrials.govStudy
Brain Connectivity in Depression
Michael D. Fox, M.D.,Ph.D. 2018. "Brain Connectivity in Depression". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT03276793.
~9 spots leftby Apr 2025
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