Behavioural Intervention

Healthy Minds Program for Depression

University of Wisconsin, Madison, WI Verified
Targeting 2 different conditionsHealthy Minds ProgramN/ARecruitingLed by Richard DavidsonResearch Sponsored by University of Wisconsin, Madison

Study Summary

This trial will test if the Healthy Minds Program app can help promote well-being in adults with depression symptoms.

Eligible Conditions
  • Depression
  • Psychological Distress

Eligibility Criteria

Inclusion Criteria

You will be eligible if you check “Yes” for the criteria below
You must be either a citizen of the United States or have permanent residency in the United States in order to receive payment.
You must be able to speak and understand English well.
You understand the study and agree to participate in it.
You are feeling sad and not enjoying your usual activities.
You need to have a smartphone that can download apps from Google Play or the Apple App Store.
You have never experienced episodes of severe mental illness, such as psychosis or mania.


Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~week 1, week 2, week 3, week 4, and 3-month follow-up
This trial's timeline: 3 weeks for screening, Varies for treatment, and week 1, week 2, week 3, week 4, and 3-month follow-up for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Change in Depression Symptoms Measured by Patient Health Questionnaire - 8 (PHQ-8) Score
Secondary outcome measures
Change in Anxiety Symptoms Measured by Generalized Anxiety Disorder - 7 (GAD-7) Score
Change in Awareness Measured by Five Facet Mindfulness Questionnaire Acting with Awareness Subscale Score
Change in Climate Change Anxiety Scale
+16 more
Other outcome measures
Change in Digital Working Alliance Inventory
Change in Facial Behavior
Change in Inclusion of Nature in Self
+10 more

Awards & Highlights

No Placebo-Only Group
All patients enrolled in this study will receive some form of active treatment.

Trial Design

3Treatment groups
Experimental Treatment
Active Control
Group I: Healthy Minds Program (HMP) appExperimental Treatment1 Intervention
Participants will receive access to the 4-week HMP Foundations module. The HMP app is a meditation-based smartphone app designed to promote and protect psychological well-being through sustainable skills training. The program is grounded in constituents of psychological well-being identified in empirical literature. HMP provides core content, with instruction administered through a curriculum of guided practices. HMP is based on research on eudaimonic well-being (e.g., environmental mastery, purpose) and brain-based skills that underlie these qualities (e.g., regulation of attention, mental flexibility). The full HMP has guided audio practices that address 4 constituents of well-being: awareness, connection, insight, and purpose. At post-treatment, participants will be given access to additional HMP content to support their continued practice.
Group II: Psychoeducation appActive Control1 Intervention
Participants will receive access to the 4-week HMP Foundations module with guided meditation practices removed. The active control will include only the didactic content included in HMP without the guided meditation practices.
Group III: Usual CareActive Control1 Intervention
Participants will receive access to HMP at the end of the study and will be encouraged to continue with their usual care.

Find a site

Who is running the clinical trial?

University of Wisconsin, MadisonLead Sponsor
1,118 Previous Clinical Trials
2,935,385 Total Patients Enrolled
16 Trials studying Depression
8,169 Patients Enrolled for Depression
Hope for Depression Research FoundationOTHER
2 Previous Clinical Trials
45 Total Patients Enrolled
2 Trials studying Depression
45 Patients Enrolled for Depression
National Center for Complementary and Integrative Health (NCCIH)NIH
808 Previous Clinical Trials
665,690 Total Patients Enrolled
59 Trials studying Depression
31,573 Patients Enrolled for Depression
Richard DavidsonPrincipal Investigator
UW-Madison, Center for Healthy Minds
Simon Goldberg, PhDPrincipal Investigator
UW-Madison, Center for Healthy Minds
2 Previous Clinical Trials
475 Total Patients Enrolled
1 Trials studying Depression
92 Patients Enrolled for Depression

Media Library

Healthy Minds Program (Behavioural Intervention) Clinical Trial Eligibility Overview. Trial Name: NCT05183867 — N/A
Depression Research Study Groups: Healthy Minds Program (HMP) app, Psychoeducation app, Usual Care
Depression Clinical Trial 2023: Healthy Minds Program Highlights & Side Effects. Trial Name: NCT05183867 — N/A
Healthy Minds Program (Behavioural Intervention) 2023 Treatment Timeline for Medical Study. Trial Name: NCT05183867 — N/A
Depression Patient Testimony for trial: Trial Name: NCT05183867 — N/A

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Who has the prerequisites to join this scientific experiment?

"This study is recruiting roughly 1500 participants who are aged 18 to 65 years old and have depression. Qualified individuals should consider applying for this trial."

Answered by AI

Does this clinical experiment have an age restriction, and if so can those over 50 apply?

"This clinical trial is open to adults between the age of 18 and 65."

Answered by AI

Are there any opportunities for new participants to join this experiment?

"Indeed, the information available on confirms that this study is still actively seeking participants as of August 8th 2022. Initially posted in March 24th 2021, it requires 1500 patients to be recruited from a single medical centre."

Answered by AI

How many individuals have signed up to participate in this experiment?

"Affirmative. According to data on, this clinical trial is currently recruiting participants; first posted on March 24th 2022, and last updated August 8th 2022. To be successful, the study requires 1500 volunteers from a single medical centre."

Answered by AI

Who else is applying?

What state do they live in?
How old are they?
18 - 65
What site did they apply to?
University of Wisconsin
What portion of applicants met pre-screening criteria?
Met criteria
Did not meet criteria
How many prior treatments have patients received?

Why did patients apply to this trial?

I need someone to talk to. Currently in very depressed condition. Looking for anything that might help me.
I want to feel better and make money doing it. I take Prozac and I still struggle with depression.

What questions have other patients asked about this trial?

Any sites in my area? Is this ok to do online? However long they need to? Are travel expenses covered?
Do you pay for transportation?

How responsive is this trial?

Typically responds via
Phone Call
Most responsive sites:
  1. University of Wisconsin: < 24 hours
Average response time
  • < 2 Days
~481 spots leftby Dec 2024