Family Cognitive Behavioral Prevention for Depression

Phase-Based Progress Estimates
1
Effectiveness
1
Safety
Vanderbilt University, Nashville, TN
Depression+1 More
Family Cognitive Behavioral Prevention - Behavioral
Eligibility
< 18
All Sexes
Eligible conditions
Select

Study Summary

This study is evaluating whether a family intervention can prevent depression in children and parents.

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Eligible Conditions

  • Depression

Treatment Effectiveness

Effectiveness Estimate

1 of 3

Study Objectives

This trial is evaluating whether Family Cognitive Behavioral Prevention will improve 1 primary outcome and 3 secondary outcomes in patients with Depression. Measurement will happen over the course of 12 months.

12 months
Children: depressive diagnoses
In children, level of internalizing and externalizing symptoms on the Child Behavior Checklist completed by parent about the child
Parents: Patient Health Questionnaire - 9 (PHQ-9)
twelve months post baseline
In children, the is level of symptoms on the Youth Self-report form.

Trial Safety

Trial Design

2 Treatment Groups

Written Information
1 of 2
Family Cognitive Behavioral Prevention
1 of 2
Active Control
Experimental Treatment

This trial requires 250 total participants across 2 different treatment groups

This trial involves 2 different treatments. Family Cognitive Behavioral Prevention is the primary treatment being studied. Participants will all receive the same treatment. There is no placebo group. The treatments being tested are not being studied for commercial purposes.

Family Cognitive Behavioral Prevention
Behavioral
A family cognitive behavioral program for parents and children. Parents learn parenting skills and cognitive behavioral techniques for managing depression. Children learn coping skills.
Written Information
Behavioral
Families receive written materials about depression and the effects of parental depression on children.

Trial Logistics

Trial Timeline

Approximate Timeline
Screening: ~3 weeks
Treatment: Varies
Reporting: twelve months post baseline
This trial has the following approximate timeline: 3 weeks for initial screening, variable treatment timelines, and roughly twelve months post baseline for reporting.

Who is running the study

Principal Investigator
J. G.
Prof. Judith Garber, Professor
Vanderbilt University

Closest Location

Vanderbilt University - Nashville, TN

Eligibility Criteria

This trial is for patients born any sex aged 18 and younger. There are 2 eligibility criteria to participate in this trial as listed below.

Mark “yes” if the following statements are true for you:
A parent with a current or history of a depressive disorder within their child's life is at a higher risk for their child to develop a depressive disorder. show original
Children ages 9- to 15-years-old

Patient Q&A Section

What are common treatments for depression?

"The options for mood disorders are limited in general but have greater promise for patients who struggle with treatment-resistant depression and who are willing and able to accept the side effects of some of the drug therapies. Of the therapies available, medication and psychotherapy are usually effective. However, patients with major depression can suffer long-term side effects. A variety of treatments can help control the course of the disorder. If treatment trials prove less effective for some patients, medication may eventually be the treatment of choice." - Anonymous Online Contributor

Unverified Answer

What are the signs of depression?

"A diagnosis of major depression is made if the patient experiences at least one of the six criteria: depressed mood for two weeks or longer, loss of interest or pleasure in usual occupations, lowered energy, fatigue, insomnia, and decreased appetite. Patients may be diagnosed with minor depression if they meet the same criteria, but do not experience significant loss of interest or pleasure in everyday activities such as household activities and social life, or when symptoms are present for only one week." - Anonymous Online Contributor

Unverified Answer

What is depression?

"Depression, which affects over a million people annually in the United Kingdom, is a mood disorder in which the sufferer has persistent sadness and loss of interest. It is an emotion that is often triggered by some real or perceived stress. Unlike other mood disorders such as anxiety or panic, there is no single cause to depression. Depression can often be treated by addressing the underlying causes. Psychological factors are crucial to a person's well being and should not be ignored." - Anonymous Online Contributor

Unverified Answer

What causes depression?

"Previous research had found that depression is related to a host of personal, social and occupational factors that are probably inter-related. It was shown by Cox et al. that unemployment and a low rank, unemployment and a low job position were both correlated with depression. These factors appear to be indicative of the type of job that the man is doing and their ability to perform the job. Some other personal factors were also shown to be associated with depression. It was found that the patient who had a poor early upbringing had a greater risk of depression. Another factor of personal cause found by Cox was the use of tranquillisers in the early development of the patients. Cox et al." - Anonymous Online Contributor

Unverified Answer

Can depression be cured?

"We may consider some other ways not to treat depression that are better aimed to improve quality of life in patients with this debilitating disease. First, depression's cause is not addressed. Second, mental health is not tackled in its roots. Third, treatments for depression are not specific." - Anonymous Online Contributor

Unverified Answer

How many people get depression a year in the United States?

"According to the American Community Survey in 2009, there were about 18 million people who had one major depression of the year in the United States, and about 35 million had two major depression episodes. A year's worth of work per person in the United States would have to be lost if at least a 15% increase in the number of individuals suffering from one or more episodes of major depression occurred for an entire year." - Anonymous Online Contributor

Unverified Answer

How does family cognitive behavioral prevention work?

"This is an innovative approach for disseminating the FCP program into the pediatric emergency department and supports evidence that we should routinely incorporate elements of interventions that aim to reduce high rates of relapse and enhance psychosocial outcomes among pediatric patients with depressive or bipolar disorder." - Anonymous Online Contributor

Unverified Answer

Does family cognitive behavioral prevention improve quality of life for those with depression?

"Families of individuals with depression have difficulty providing care when that individual has clinically significant depression. This may represent a problem of family functioning that, in turn, results in a disruption in the continuity of services. Our intervention showed some improvement in family functioning and in depressive symptoms for those with significant depression." - Anonymous Online Contributor

Unverified Answer

What is the primary cause of depression?

"There is a need for the development of a research framework which can assess the various contributory causal factors involved\n\n1. Primary – medical diagnosis\n2. Secondary – psychiatric diagnosis\n3." - Anonymous Online Contributor

Unverified Answer

What is family cognitive behavioral prevention?

"Family counseling is a useful adjunct to current pediatric depression management, and is a particularly effective tool for achieving remission in children, adolescents and young adults with major depressive episodes. Effective FCPs must take the pediatric and familial dimensions into consideration to address prevention and maintenance." - Anonymous Online Contributor

Unverified Answer

Does depression run in families?

"The present results are consistent with all of the currently known risk factors for depression and suggest that it is possible to identify individuals at risk of this disabling disorder before the clinical diagnosis can be made. There is an urgent need to identify and modify the major risk loci and their associated genes." - Anonymous Online Contributor

Unverified Answer

Is family cognitive behavioral prevention safe for people?

"Findings suggest that if family risk factors and family interventions had been available, rates of problem-free treatment would have been lower than reported in the literature. People would not have been referred as ineffectively as some might have been. Thus, prevention and intervention is important but not enough to translate into reduced health in populations high at risk." - Anonymous Online Contributor

Unverified Answer
Please Note: These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.
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