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Brain Stimulation

Transcranial direct current stimulation (tDCS) for Depression

N/A
Waitlist Available
Led By Leigh Charvet, MD
Research Sponsored by NYU Langone Health
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be between 18 and 65 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up study tdcs administration visit (day1), pre-tdcs administration time (1 hour)
Awards & highlights

Study Summary

This trial will test whether a single session of transcranial direct current stimulation (tDCS) to the dorsolateral prefrontal cortex (DLPFC) can reduce depression-related attention bias in patients with mild to moderate depression.

Eligible Conditions
  • Depression

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~study tdcs administration visit (day1), pre-tdcs administration time (1 hour)
This trial's timeline: 3 weeks for screening, Varies for treatment, and study tdcs administration visit (day1), pre-tdcs administration time (1 hour) for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Analog Mood Scale (AMS) Anxiety Score
Analog Mood Scale (AMS) Happy Score
Analog Mood Scale (AMS) Sad Score
+4 more

Trial Design

1Treatment groups
Experimental Treatment
Group I: Female participants with DepressionExperimental Treatment1 Intervention
Female participants with mild to moderate depression to determine if a single-session of tDCS can alter negative attention bias. The primary objective is to study if single-session tDCS will affect attention bias in depression and is not meant to treat depression.
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
Transcranial direct current stimulation (tDCS)
2016
Completed Phase 3
~820

Find a Location

Who is running the clinical trial?

NYU Langone HealthLead Sponsor
1,367 Previous Clinical Trials
839,740 Total Patients Enrolled
21 Trials studying Depression
1,481 Patients Enrolled for Depression
Leigh Charvet, MDPrincipal InvestigatorNYU Langone Health
7 Previous Clinical Trials
378 Total Patients Enrolled

Media Library

Transcranial direct current stimulation (tDCS) (Brain Stimulation) Clinical Trial Eligibility Overview. Trial Name: NCT05188248 — N/A
Depression Research Study Groups: Female participants with Depression
Depression Clinical Trial 2023: Transcranial direct current stimulation (tDCS) Highlights & Side Effects. Trial Name: NCT05188248 — N/A
Transcranial direct current stimulation (tDCS) (Brain Stimulation) 2023 Treatment Timeline for Medical Study. Trial Name: NCT05188248 — N/A
Depression Patient Testimony for trial: Trial Name: NCT05188248 — N/A

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Are there opportunities available for individuals to enroll in this trial?

"Affirmative, the details on clinicaltrials.gov confirm that recruitment for this trial has commenced. This study was first listed on December 15th 2021 and revised as recently as November 22nd 2022. 75 patients are currently being enrolled at a single site."

Answered by AI

Does this research endeavor solicit individuals aged sixty and over?

"To be eligible for this study, the patient must fall between 18 to 45 years old. For those under 18 or over 65, there are 192 and 963 trials respectively that may fit their criteria."

Answered by AI

How many participants has this clinical trial recruited thus far?

"Affirmative. According to details found on clinicaltrials.gov, enrollment for this medical trial is currently underway. It was originally posted on December 15th 2021 and underwent its most recent update November 22nd 2022. The research requires 75 participants from a single location of study."

Answered by AI

Who would be the ideal candidate to partake in this research endeavor?

"This investigation is recruiting 75 participants with depression, aged 18-45. Prerequisites for enrollment include being female and having moderately significant to severe symptoms as indicated by BDI-II scores between 14-19 or 20-28 if on stable pharmalogic medication at least 30 days prior to screening."

Answered by AI

Who else is applying?

What state do they live in?
North Carolina
Connecticut
Other
New York
How old are they?
65+
18 - 65
What site did they apply to?
NYU Langone Health
What portion of applicants met pre-screening criteria?
Met criteria
How many prior treatments have patients received?
3+

Why did patients apply to this trial?

I've tried SSRIs and CBT with mild effect. MDD remains recurrent.
PatientReceived no prior treatments

How responsive is this trial?

Typically responds via
Email
Most responsive sites:
  1. NYU Langone Health: < 48 hours
Average response time
  • < 2 Days
Recent research and studies
clinicaltrials.govStudy
A Pilot Study of the Immediate Effects of DLPFC tDCS on Attention Bias in Depression
2021. "A Pilot Study of the Immediate Effects of DLPFC tDCS on Attention Bias in Depression". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT05188248.
~6 spots leftby Apr 2025
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