← Back to Search

CAD/CAM Dental Restorations for Tooth Decay

N/A

Waitlist Available

Research Sponsored by 3M

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Subject in need of crown and/or onlay restoration

Subject age 18 or above

Timeline

Screening 3 weeks

Treatment Varies

Follow Up 3 years

Awards & highlights

Study Summary

This trial will study the long-term performance of a resin cement used for chairside CAD/CAM restorations.

Who is the study for?

This trial is for adults over 18 with healthy or treated gums who need a crown or onlay restoration. They must agree to participate and be available for the study duration. It's not for those allergic to products used, have devital/sensitive teeth, untreated dental issues, prior endodontic treatment, incomplete tooth fractures, pulp capping history, or uncontrolled teeth grinding.Check my eligibility

What is being tested?

The trial is testing two types of chairside CAD/CAM restorations: zirconia crowns (3M) cemented with self-adhesive resin and lithium disilicate onlays (IPS emaxCAD/Ivoclar) bonded using selective enamel etch technique. The goal is to compare their long-term clinical performance.See study design

What are the potential side effects?

Potential side effects may include sensitivity in the restored tooth, allergic reactions to materials used in restorations or adhesives/cements involved in the procedure. Long-term complications could involve issues with the fit or durability of the restoration.

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below

Select...

I need a dental crown or onlay.

Select...

I am 18 years old or older.

Select...

My gums are healthy or treated, with minimal tooth movement.

Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ 3 years

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~3 years

This trial's timeline: 3 weeks for screening, Varies for treatment, and 3 years for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.

Primary outcome measures

Biologic properties of restorations (onlays and crowns) [Change from baseline]

Esthetic properties of restorations (onlays and crowns) [Change from baseline]

Functional long-term properties clinical performance of restorations (onlays and crowns) [Change from baseline]

+1 more

Secondary outcome measures

Gingival index

Plaque index

Trial Design

2Treatment groups

Experimental Treatment

Group I: CAD/CAM OnlaysExperimental Treatment1 Intervention

Lithium disilicate chairside CAD/CAM onlays (IPS emaxCAD/Ivoclar) will be adhesively bonded using a selective enamel etch technique with an adhesive (3M) and cement (3M).

Group II: CAD/CAM CrownsExperimental Treatment1 Intervention

Full contour zirconia crowns (3M Chairside Zirconia/3M) will be cemented using a self-adhesive cement (3M).

0 / 3Eligibility criteria met

Find a Location

Who is running the clinical trial?

University of MichiganOTHER

1,795 Previous Clinical Trials

6,373,878 Total Patients Enrolled

3MLead Sponsor

157 Previous Clinical Trials

31,416 Total Patients Enrolled

Bernadette RauchStudy Director3M

Media Library

Chairside zirconia crowns (3M) Clinical Trial Eligibility Overview. Trial Name: NCT04279574 — N/A

Tooth Decay Research Study Groups: CAD/CAM Crowns, CAD/CAM Onlays

Tooth Decay Clinical Trial 2023: Chairside zirconia crowns (3M) Highlights & Side Effects. Trial Name: NCT04279574 — N/A

Chairside zirconia crowns (3M) 2023 Treatment Timeline for Medical Study. Trial Name: NCT04279574 — N/A

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

May I be considered for inclusion in this research program?

"In this research initiative, we are recruiting a cohort of 60 subjects aged 18-89 with existing dental cements. The inclusion criteria also dictates that the patients must be in need of either crown or onlay restoration treatments."

Answered by AI

Are there any open enrollment opportunities for this trial presently?

"Per clinicaltrials.gov, recruitment for this trial ceased after the November 4th 2021 update. This investigation was first announced on August 26 2020; however, there are presently 103 active trials enrolling patients at present."

Answered by AI

Does this experiment seek to include participants of 40 years and up?

"To be eligible for this trial, applicants must between the ages of 18 and 89. Additionally, there are 55 medical studies specifically dedicated to those under 18 years old and 31 such trials targeting individuals above 65."

Answered by AI