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Intervention for Palliative Care

N/A
Waitlist Available
Research Sponsored by Wayne State University
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Patients undergoing ventilator withdrawal
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up change from baseline through repeated measures up to 8 hours
Awards & highlights

Study Summary

This trial will test a new method for withdrawing ventilation from terminally ill patients in order to improve patient comfort while ensuring effective use of opioids and/or benzodiazepines.

Eligible Conditions
  • Palliative Care
  • Critical Care

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~change from baseline through repeated measures up to 8 hours
This trial's timeline: 3 weeks for screening, Varies for treatment, and change from baseline through repeated measures up to 8 hours for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Patient respiratory comfort

Trial Design

2Treatment groups
Active Control
Group I: ControlActive Control1 Intervention
The medical intensive care unit in four hospitals will comprise the clusters. All four clusters begin the study under the control condition. Ventilator withdrawal is conducted by the usual personnel in those units. Data is collected through observation of the process and the respiratory comfort of the enrolled patients. Each cluster is randomly selected to sequentially cross over to the intervention. The remaining clusters continue with usual care (control) until selected for crossover.
Group II: InterventionActive Control1 Intervention
Each cluster is randomly selected to sequentially crossover to the intervention. When crossed over to the intervention the assigned intensive care nurse conducts the ventilator withdrawal according to the algorithm. The algorithm is informed by an objective measure of patient respiratory comfort. Data is collected through observation of the process and the respiratory comfort of the enrolled patients.

Find a Location

Who is running the clinical trial?

National Institute of Nursing Research (NINR)NIH
577 Previous Clinical Trials
10,375,648 Total Patients Enrolled
8 Trials studying Palliative Care
1,510 Patients Enrolled for Palliative Care
Wayne State UniversityLead Sponsor
307 Previous Clinical Trials
108,299 Total Patients Enrolled

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.
Recent research and studies
clinicaltrials.govStudy
An Algorithmic Approach to Ventilator Withdrawal at the End of Life
Margaret Campbell 2017. "An Algorithmic Approach to Ventilator Withdrawal at the End of Life". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT03121391.
~21 spots leftby Apr 2025
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