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Procedure

Heart Transplantation for Death (DCDNRPHeart Trial)

N/A
Waitlist Available
Led By Marian Urban, MD, PhD
Research Sponsored by University of Nebraska
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up date from the first dcd nrp heart procurement until the 25th dcd nrp heart procurement, assessed up to 36 months
Awards & highlights

DCDNRPHeart Trial Summary

This trial will test whether it is feasible to transplant hearts using a method that keeps the organs warm and functioning.

Eligible Conditions
  • Death
  • Heart Transplant
  • Determination of Death
  • Outcomes Research

DCDNRPHeart Trial Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~date from the first dcd nrp heart procurement until the 25th dcd nrp heart procurement, assessed up to 36 months
This trial's timeline: 3 weeks for screening, Varies for treatment, and date from the first dcd nrp heart procurement until the 25th dcd nrp heart procurement, assessed up to 36 months for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Utilization rate
Secondary outcome measures
Acute cellular rejection (ACR)
Antibody mediated rejection (AMR)
Graft survival
+1 more

DCDNRPHeart Trial Design

1Treatment groups
Experimental Treatment
Group I: Donors After Circulatory Determined deathExperimental Treatment1 Intervention
Recipients receiving an organ from donors after circulatory determined death
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
Heart Transplantation
2021
N/A
~10

Find a Location

Who is running the clinical trial?

University of NebraskaLead Sponsor
539 Previous Clinical Trials
1,144,724 Total Patients Enrolled
4 Trials studying Death
7,363 Patients Enrolled for Death
Marian Urban, MD, PhDPrincipal Investigator - Assistant Professor
University of Nebraska
1 Previous Clinical Trials
5 Total Patients Enrolled
1 Trials studying Death
5 Patients Enrolled for Death

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.
Recent research and studies
The Journal of Heart and Lung TransplantationJournal
Human Heart Transplantation from Donation After Circulatory-determined Death Donors Using Normothermic Regional Perfusion and Cold Storage
Messer, Simon, Aravinda Page, Simon Colah, Richard Axell, Barbora Parizkova, Steven Tsui, and Stephen Large. 2018. “Human Heart Transplantation from Donation After Circulatory-determined Death Donors Using Normothermic Regional Perfusion and Cold Storage”. The Journal of Heart and Lung Transplantation. Elsevier BV. doi:10.1016/j.healun.2018.03.017.
South African Medical JournalJournal
Transplantation of the Heart: An Overview of 40 Years' Clinical and Research Experience at Groote Schuur Hospital and the University of Cape Town: Part I. Surgical Experience and Clinical Studies
Hassoulas, J. 2012. “Transplantation of the Heart: An Overview of 40 Years' Clinical and Research Experience at Groote Schuur Hospital and the University of Cape Town: Part I. Surgical Experience and Clinical Studies”. South African Medical Journal. South African Medical Association NPC. doi:10.7196/samj.5020.
Current Opinion in Organ TransplantationJournal
Donation After Circulatory Death Heart Transplantation
Dhital, Kumud K., Hong C. Chew, and Peter S. Macdonald. 2017. “Donation After Circulatory Death Heart Transplantation”. Current Opinion in Organ Transplantation. Ovid Technologies (Wolters Kluwer Health). doi:10.1097/mot.0000000000000419.
Journal of the American College of CardiologyJournal
Outcomes of Donation After Circulatory Death Heart Transplantation in Australia
Chew, Hong Chee, Arjun Iyer, Mark Connellan, Sarah Scheuer, Jeanette Villanueva, Ling Gao, Mark Hicks, et al.. 2019. “Outcomes of Donation After Circulatory Death Heart Transplantation in Australia”. Journal of the American College of Cardiology. Elsevier BV. doi:10.1016/j.jacc.2018.12.067.
~2 spots leftby Apr 2025
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