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IPD Probe for Gut Permeability

N/A
Recruiting
Led By Guillermo Tearney, M.D, PhD.
Research Sponsored by Massachusetts General Hospital
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Subject must be able to consent to the procedure
Subject must be 18 to 60 years of age
Timeline
Screening 3 weeks
Treatment Varies
Follow Up imaging data is collected during the procedure, and analyzed within 1 year of collection.
Awards & highlights

Study Summary

This trial is testing whether a trans-nasal IPD probe can be used to measure gut permeability.

Who is the study for?
This trial is for healthy adults aged 18-60 who can consent and fast for at least 8 hours. It's not suitable for those with respiratory diseases, nasal steroid use, gastric emptying delays, alcoholism, certain medication uses (like clotting impairments or mast cell stabilizers), recent antibiotics use, liver diseases, galactosemia, uncontrolled diabetes, lactation due to pregnancy or any contraindications to nasopharyngeal procedures.Check my eligibility
What is being tested?
The study is testing the feasibility of a trans-nasal IPD probe as a tool to measure gut permeability. Participants will undergo this minimally invasive procedure where the probe is inserted through the nose to assess intestinal function.See study design
What are the potential side effects?
Potential side effects may include discomfort from the nasal insertion of the probe and possible irritation in the nose or throat. There might also be risks associated with fasting and reactions specific to individual health conditions.

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below
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I can understand and agree to the treatment plan.
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I am between 18 and 60 years old.

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~imaging data is collected during the procedure, and analyzed within 1 year of collection.
This trial's timeline: 3 weeks for screening, Varies for treatment, and imaging data is collected during the procedure, and analyzed within 1 year of collection. for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Baseline IPD readings
IPD readings after Glucose/Galactose infusion
Image Quality

Trial Design

1Treatment groups
Experimental Treatment
Group I: Feasibility of trans-nasal IPD probeExperimental Treatment1 Intervention
The purpose of this study is to examine the feasibility of using a trans-nasal IPD probe as a measurement tool for gut permeability

Find a Location

Who is running the clinical trial?

Massachusetts General HospitalLead Sponsor
2,924 Previous Clinical Trials
13,193,413 Total Patients Enrolled
Guillermo Tearney, M.D, PhD.Principal Investigator - Massachusetts General Hospital
Massachusetts General Hospital
6 Previous Clinical Trials
630 Total Patients Enrolled

Media Library

IPD Probe via TNIT Clinical Trial Eligibility Overview. Trial Name: NCT04565821 — N/A
Crohn's Disease Clinical Trial 2023: IPD Probe via TNIT Highlights & Side Effects. Trial Name: NCT04565821 — N/A
IPD Probe via TNIT 2023 Treatment Timeline for Medical Study. Trial Name: NCT04565821 — N/A
Crohn's Disease Research Study Groups: Feasibility of trans-nasal IPD probe

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Is the minimum age requirement for participation in this trial below 50 years old?

"The cutoff age for this medical trial is 60 years old, with a lower limit of 18."

Answered by AI

Am I eligible to enroll in this clinical trial?

"This medical experiment requires prospective participants to have an inflammatory bowel disorder and be within the 18-60 age bracket. Approximately 10 candidates will be accepted into this clinical trial."

Answered by AI

How many participants are actively involved in this research project?

"Affirmative. Details accessible on clinicaltrials.gov demonstrate that this medical trial has resumed recruitment, which began 11/12/2020 and was most recently updated 7/21/2021. 10 participants must be sourced from a single location to join the study."

Answered by AI

Are there any openings for this research effort currently available?

"Clinicaltrials.gov discloses that this research is currently seeking volunteers; the trial was opened on November 12th 2020, with its most recent amendment made on July 21st 2021."

Answered by AI
~2 spots leftby Mar 2025