COVID-19 self-test for COVID-19

Phase-Based Progress Estimates
1
Effectiveness
1
Safety
Public Health Management Corporation, Philadelphia, PA
COVID-19+1 More
COVID-19 self-test - Behavioral
Eligibility
18+
All Sexes
What conditions do you have?
Select

Study Summary

COVID-19 Close Contact Self-Testing Study

See full description

Eligible Conditions

  • COVID-19
  • Covid19

Treatment Effectiveness

Effectiveness Progress

1 of 3

Study Objectives

This trial is evaluating whether COVID-19 self-test will improve 1 primary outcome and 5 secondary outcomes in patients with COVID-19. Measurement will happen over the course of 8 weeks.

8 weeks
Number of contacts tested
Number of household contacts tested
Number of positive contacts
Through study completion, up to one year
Number of contacts tested (end of study)
Number of household contacts tested (end of study)
Number of positive contacts (end of study)

Trial Safety

Safety Progress

1 of 3

Trial Design

2 Treatment Groups

Test referral distribution
1 of 2
Self-Test kit distribution
1 of 2
Active Control
Experimental Treatment

This trial requires 210 total participants across 2 different treatment groups

This trial involves 2 different treatments. COVID-19 Self-test is the primary treatment being studied. Participants will all receive the same treatment. There is no placebo group. The treatments being tested are not being studied for commercial purposes.

Self-Test kit distribution
Behavioral
Participants in the self-test arm receive multiple COVID-19 self-test kits to distribute to their close contacts.
Test referral distribution
Behavioral
Participants in the test referral arm receive text messages providing testing information to send to their close contacts.

Trial Logistics

Trial Timeline

Approximate Timeline
Screening: ~3 weeks
Treatment: Varies
Reporting: through study completion, up to one year
This trial has the following approximate timeline: 3 weeks for initial screening, variable treatment timelines, and roughly through study completion, up to one year for reporting.

Who is running the study

Principal Investigator
R. G.
Prof. Robert Gross, Professor of Medicine
University of Pennsylvania

Closest Location

Public Health Management Corporation - Philadelphia, PA

Eligibility Criteria

This trial is for patients born any sex aged 18 and older. There are 3 eligibility criteria to participate in this trial as listed below.

Mark “yes” if the following statements are true for you:
18 years of age or older
Has a working telephone number
Willing and able to provide informed consent

Patient Q&A Section

Can covid-19 be cured?

"There remains a need for more evidence that SARS-CoV2 or its virus-like particles can be prevented and/or treated. In the meantime, there are no recommendations for the prevention, treatment or cure of SARS-CoV2 or its virus-like particles. However, the available antiviral drugs can be used in clinical trials to test their ability to protect from or treat SARS-CoV2 infection. Such trials need to be carefully designed and reported to ensure that any beneficial effects result from drug treatment and not from an unmasking of SARS-CoV2." - Anonymous Online Contributor

Unverified Answer

What are the signs of covid-19?

"Signs of infection can include fever, dry cough, headache, chills, muscle and joint ache, red eye, dryness in the throat, cough up blood, vomiting and diarrhoea. These do not appear to be persistent for more than 2 weeks. There is no clear correlation between these signs of infection and time of exposure." - Anonymous Online Contributor

Unverified Answer

What is covid-19?

"In March 2019, the World Health Organisation declared the Covid-19 (coronavirus disease 2019) outbreak to be a Global Emergency; by 9 April 2019, it had reached pandemic levels. Although the disease was already in China, the spread to other countries, specifically to the United States and Europe, was quickly tracked by the World Health Organisation (WHO). Worldwide there are about 10 million cases with more than 100,000 deaths. In China, since the outbreak began in November 2019, over 20 provinces, but especially Wuhan, are the main sites of infection, and the number of cases has skyrocketed from approximately 800 on 1 January, more than 3,300 on 4 February, and over 15,000 on 8 February." - Anonymous Online Contributor

Unverified Answer

How many people get covid-19 a year in the United States?

"There were nearly 13.6 million confirmed cases of coronavirus disease in the United States as of 23 April. This is a significant number, but represents a low percentage of the population and a low monthly incidence rate. Additionally there are approximately 3.8 million asymptomatic infections at the beginning of January. This data can be used to project future epidemic events and may assist in limiting infected contacts in the public." - Anonymous Online Contributor

Unverified Answer

What are common treatments for covid-19?

"Anticandival drugs, such as oseltamivir and lopinavir, are used to control acute viral flare and to prevent and decrease mortality. Other interventions, such as mechanical ventilation, oxygen infusion and noninvasive ventilation are prescribed to treat the pulmonary complication in severe cases of pandemic pneumonia. Additional drugs and treatments, such as steroid, antiviral treatment and blood replenishment, are prescribed by many hospitals." - Anonymous Online Contributor

Unverified Answer

What causes covid-19?

"The most likely risk factor for contracting COVID-19 is having close contact with someone infected with SARS-CoV-2. Since the first confirmed SARS-CoV-2 case in China was an imported student from Wuhan, China, there are questions surrounding whether the current outbreak in Wuhan is a result of human-to-human transmission of SARS-CoV-2. In an article published by the "New England Journal of Medicine" a possible way SARS-CoV-2 was brought to Wuhan, China could have been through animal-to-human transmission." - Anonymous Online Contributor

Unverified Answer

How serious can covid-19 be?

"There are a number of risk factors for complications from covid-19, including age, chronic lung disease, diabetes, and heart disease. Risk factors for covid-19 related complications include the presence of other medical comorbidities and living in an area that's recently reported with confirmed cases of covid-19 infection. It's important to keep in mind of the risk of severe complications associated with covid-19 throughout the month of March 2020, especially if you are of older, or at risk for medical conditions such as heart disease." - Anonymous Online Contributor

Unverified Answer

Have there been other clinical trials involving covid-19 self-test?

"None of the publications provided data justifying in favor or against the use of the covid-19 self-test in clinical settings. There are limitations with self-testing as an alternative to laboratory testing for covid-19; however, further evaluation of its use is required." - Anonymous Online Contributor

Unverified Answer

What are the latest developments in covid-19 self-test for therapeutic use?

"The first case of therapeutic use in Europe is that of a 44-year-old patient hospitalized in the Neurology Department of a tertiary hospital with COVID-19. This case is very interesting and shows that in this region, self-testing of patients with COVID-19 and/or IgM-IGG specific antibody for SARS-CoV-2 can be done safely with a low rate of false positives/negatives and, in some cases, a better specificity than a standard IgM-IgG-based test." - Anonymous Online Contributor

Unverified Answer

Does covid-19 run in families?

"Results from this study and those reported in the literature and the literature review imply that in familial cases of covid-19-induced pneumonia, a history of a family member having covid-19-induced pneumonia may not be present in a large part of cases. Furthermore, family members of cases with viral pneumonia may not be infectious. Results from a recent clinical trial can have clinical implications and highlight the importance of close family contact of patients with viral pneumonia or influenza." - Anonymous Online Contributor

Unverified Answer

What is the average age someone gets covid-19?

"This is a global overview; the data can be used to calculate more precisely the average age people get the disease. The average age is around 40. For every 5 years of life lost due to the disease, a person is estimated to gain 3 years, which means the average is 43. The table below gives estimates for countries with high levels of morbidity:\n\nTable 2: Average Age at Onset in Countries with High Morbidity due to Coronavirus Infection\n\nIn 2019 the WHO estimated 7.1 million cases of coronavirus infection and an unspecified but substantial number of deaths (as of November 19, 2019)." - Anonymous Online Contributor

Unverified Answer

Is covid-19 self-test typically used in combination with any other treatments?

"The self-examination method is one of the most used methods for testing infections caused by viruses. Self-examination with testing of saliva or other bodily fluids are a good method to detect the virus because it is fast, convenient and cost-effective. However, such tests can only be used with specific instructions and guidance regarding the virus. A study in Taiwan tested self-examination to be the most effective method for screening the people who do not visit the clinic. They concluded that the self-examination method could be an effective method for screening the people or people who have a high risk of infection from the virus." - Anonymous Online Contributor

Unverified Answer
Please Note: These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.
See if you qualify for this trial
Get access to this novel treatment for COVID-19 by sharing your contact details with the study coordinator.