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Probiotics for COVID-19 (PIRATES-COV Trial)

N/A
Waitlist Available
Research Sponsored by Université de Sherbrooke
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be older than 65 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up 6 months
Awards & highlights

PIRATES-COV Trial Summary

This trialwill test if taking probiotics before & after a 4th COVID vaccine dose could offer seniors better protection against the virus. #COVID19 #elderly #vaccine #probiotics

Who is the study for?
This trial is for seniors aged 65-89 who've had 3 doses of an mRNA COVID vaccine and are up for a fourth. They must be in good cognitive health, not have had COVID-19, and live close to the research center if they're part of the subgroup. Those with allergies or weakened immune systems can't join.Check my eligibility
What is being tested?
The study tests if probiotics can boost long-term protection from a fourth COVID vaccine dose in the elderly. Participants will take a daily capsule (probiotic or placebo) around their vaccination time and send blood samples for antibody testing over six months.See study design
What are the potential side effects?
Probiotics are generally safe with few side effects; however, some may experience digestive discomfort like gas or bloating. The study aims to confirm this safety profile alongside any potential benefits.

PIRATES-COV Trial Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~6 months
This trial's timeline: 3 weeks for screening, Varies for treatment, and 6 months for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Decreasing of 33% the percentage of elders without Receptor-Binding Domain (RBD) antibodies, 6 months after the vaccine booster shot

PIRATES-COV Trial Design

2Treatment groups
Experimental Treatment
Placebo Group
Group I: ProbioticsExperimental Treatment1 Intervention
taking a capsule containing the probiotics 15 d before and 15 d after booster shot.
Group II: ControlPlacebo Group1 Intervention
taking a capsule containing a placebo 15 d before and 15 d after booster shot.

Find a Location

Who is running the clinical trial?

Université de SherbrookeLead Sponsor
292 Previous Clinical Trials
68,849 Total Patients Enrolled
4 Trials studying COVID-19
1,406 Patients Enrolled for COVID-19
CHU de Quebec-Universite LavalOTHER
167 Previous Clinical Trials
106,565 Total Patients Enrolled
3 Trials studying COVID-19
1,207 Patients Enrolled for COVID-19
Jean-Charles Pasquier, DrStudy DirectorUniversité de Sherbrooke
1 Previous Clinical Trials
17 Total Patients Enrolled
1 Trials studying COVID-19
17 Patients Enrolled for COVID-19

Media Library

Probiotics Clinical Trial Eligibility Overview. Trial Name: NCT05195151 — N/A
Probiotics 2023 Treatment Timeline for Medical Study. Trial Name: NCT05195151 — N/A
COVID-19 Research Study Groups: Probiotics, Control
COVID-19 Clinical Trial 2023: Probiotics Highlights & Side Effects. Trial Name: NCT05195151 — N/A

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Who can participate in this trial and qualify for the program?

"This trial is recruiting 668 individuals with COVID-19 aged 65 to 89. The necessary criteria for participants include being male or female, having already received 3 mRNA vaccine doses (Pfizer-BioNTech or Moderna) at least six months prior, agreeing to receive another dose of the vaccine, having telephone/internet access, expressing informed consent and living less than 75 km from the Clinical Research Centre (applicable only to a subset of 100 patients)."

Answered by AI

Is the recruitment process for this trial still open?

"Per the info on clinicaltrials.gov, this trial is in its recruitment phase and has been since November 10th 2022. The most recent update occurred 6 days later on November 16th 2022."

Answered by AI

What is the total number of participants being recruited for this research?

"Indeed, the information hosted on clinicaltrials.gov suggests that this medical trial is presently recruiting patients. The investigation was initially posted to the site on November 10th 2022 and last modified on November 16th 2022. 668 participants need be sourced from one centre for the study's success."

Answered by AI

Is geriatric participation accepted for this investigation?

"The terms of eligibility for this research trial indicate that the minimum age requirement is 65 and the maximum limit is 89."

Answered by AI
Recent research and studies
clinicaltrials.govStudy
Modification of the COVID-19 Vaccine Response by an Intervention on the Intestinal Flora
2022. "Modification of the COVID-19 Vaccine Response by an Intervention on the Intestinal Flora". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT05195151.
All > Covid 19 > Coronavirus
~59 spots leftby Jul 2024
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