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Lift for COVID-19 (LIFTCOVID Trial)

N/A
Waitlist Available
Led By Christopher E Cox, MD
Research Sponsored by Duke University
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up t1 (time of randomization [i.e., 1 month post-hospital discharge), t2 (2 months post-randomization [i.e., 3 months post-hospital discharge), t3 (5 months post-randomization [i.e., 6 months post-hospital discharge)
Awards & highlights

LIFTCOVID Trial Summary

This study is evaluating whether a mobile app may help reduce distress in patients with chronic obstructive pulmonary disease.

Eligible Conditions
  • COVID-19
  • Coronavirus
  • Cardiorespiratory Failure

LIFTCOVID Trial Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~t1 (time of randomization [i.e., 1 month post-hospital discharge), t2 (2 months post-randomization [i.e., 3 months post-hospital discharge), t3 (5 months post-randomization [i.e., 6 months post-hospital discharge)
This trial's timeline: 3 weeks for screening, Varies for treatment, and t1 (time of randomization [i.e., 1 month post-hospital discharge), t2 (2 months post-randomization [i.e., 3 months post-hospital discharge), t3 (5 months post-randomization [i.e., 6 months post-hospital discharge) for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Change in Patient Health Questionnaire-9 Item Scale (PHQ-9) Over 3 Months Post-discharge
Secondary outcome measures
Change in EuroQOL-5DL (Quality of Life) Scale at 3 Months Post-discharge
Change in EuroQOL-5DL (Quality of Life) Scale at 6 Months Post-discharge
Change in Generalized Anxiety Disorder 7-item Scale (GAD-7) at 3 Months Post-discharge
+4 more
Other outcome measures
Healthcare Utilization
Intervention Adherence as Measured by Percentage of Tasks Completed

LIFTCOVID Trial Design

2Treatment groups
Experimental Treatment
Active Control
Group I: Lift mobile mindfulness programExperimental Treatment1 Intervention
Will receive standard dose Lift mobile mindfulness program intervention content, app-based response to elevated symptoms, and no introductory call from a therapist. This program lasts 1 month and includes 4 unique weeks' worth of audio, video, and text content.
Group II: Usual care controlActive Control1 Intervention
Usual care.
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
Lift
2021
N/A
~60

Find a Location

Who is running the clinical trial?

National Center for Complementary and Integrative Health (NCCIH)NIH
832 Previous Clinical Trials
668,877 Total Patients Enrolled
1 Trials studying COVID-19
113 Patients Enrolled for COVID-19
Duke UniversityLead Sponsor
2,363 Previous Clinical Trials
3,420,450 Total Patients Enrolled
50 Trials studying COVID-19
356,107 Patients Enrolled for COVID-19
Christopher E Cox, MDPrincipal InvestigatorDuke University
3 Previous Clinical Trials
379 Total Patients Enrolled

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.
Recent research and studies
Contemporary Clinical TrialsJournal
Optimizing a Self-directed Mobile Mindfulness Intervention for Improving Cardiorespiratory Failure Survivors' Psychological Distress (LIFT2): Design and Rationale of a Randomized Factorial Experimental Clinical Trial
Cox, Christopher E., Maren K. Olsen, John A. Gallis, Laura S. Porter, Jeffrey M. Greeson, Tina Gremore, Allie Frear, et al.. 2020. “Optimizing a Self-directed Mobile Mindfulness Intervention for Improving Cardiorespiratory Failure Survivors' Psychological Distress (LIFT2): Design and Rationale of a Randomized Factorial Experimental Clinical Trial”. Contemporary Clinical Trials. Elsevier BV. doi:10.1016/j.cct.2020.106119.
ThoraxJournal
Effects of Mindfulness Training Programmes Delivered by a Self-directed Mobile App and by Telephone Compared with an Education Programme for Survivors of Critical Illness: A Pilot Randomised Clinical Trial
Cox, Christopher E, Catherine L Hough, Derek M Jones, Anna Ungar, Wen Reagan, Mary D Key, Tina Gremore, et al.. 2018. “Effects of Mindfulness Training Programmes Delivered by a Self-directed Mobile App and by Telephone Compared with an Education Programme for Survivors of Critical Illness: A Pilot Randomised Clinical Trial”. Thorax. BMJ. doi:10.1136/thoraxjnl-2017-211264.
Annals of the American Thoracic SocietyJournal
Development and Preliminary Evaluation of a Telephone-based Mindfulness Training Intervention for Survivors of Critical Illness
Cox, Christopher E., Laura S. Porter, Pamela J. Buck, Mary Hoffa, Derek Jones, Brenda Walton, Catherine L. Hough, and Jeffrey M. Greeson. 2014. “Development and Preliminary Evaluation of a Telephone-based Mindfulness Training Intervention for Survivors of Critical Illness”. Annals of the American Thoracic Society. American Thoracic Society. doi:10.1513/annalsats.201308-283oc.
clinicaltrials.govStudy
Lift Mobile Mindfulness for COVID-19 Distress Symptoms
2021. "Lift Mobile Mindfulness for COVID-19 Distress Symptoms". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT04581200.
~13 spots leftby Apr 2025
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