Study Summary
This trial is testing different combinations of electrical stimulations to the wrist or knee to see which is most effective at treating IBS-C.
- Constipation
- Irritable Bowel Syndrome
Treatment Effectiveness
Phase-Based Effectiveness
Study Objectives
2 Primary · 2 Secondary · Reporting Duration: VAS surveys will be taken 6 times approximately 5 minutes apart during each visit. 5 visits will occur between 1 and 3 weeks apart.
Trial Safety
Phase-Based Safety
Awards & Highlights
Trial Design
1 Treatment Group
Subjects with IBS-C
1 of 1
Experimental Treatment
23 Total Participants · 1 Treatment Group
Primary Treatment: Transcutaneous Electrical Acustimulation (TEA) · No Placebo Group · N/A
Trial Logistics
Trial Timeline
Who is running the clinical trial?
Eligibility Criteria
Age 18 - 99 · All Participants · 5 Total Inclusion Criteria
Mark “Yes” if the following statements are true for you:- Jiang, Y., J. Liu, J. Liu, J. Han, X. Wang, and C. Cui. 2014. “Cerebral Blood Flow-based Evidence for Mechanisms of Low- Versus High-frequency Transcutaneous Electric Acupoint Stimulation Analgesia: A Perfusion Fmri Study in Humans”. Neuroscience. Elsevier BV. doi:10.1016/j.neuroscience.2014.03.019.
- Qu, Fan, Fang-Fang Wang, Yan Wu, Jue Zhou, Nicola Robinson, Paul J. Hardiman, Jie-Xue Pan, et al.. 2017. “Transcutaneous Electrical Acupoint Stimulation Improves the Outcomes of in Vitro Fertilization: A Prospective, Randomized and Controlled Study”. Explore. Elsevier BV. doi:10.1016/j.explore.2017.06.004.
- Yu, Yue, Ruiling Wei, Zhi Liu, Jiaqin Xu, Chao Xu, and Jiande D.Z. Chen. 2019. “Ameliorating Effects of Transcutaneous Electrical Acustimulation Combined with Deep Breathing Training on Refractory Gastroesophageal Reflux Disease Mediated via the Autonomic Pathway”. Neuromodulation: Technology at the Neural Interface. Elsevier BV. doi:10.1111/ner.13021.
- Zhang, Bo, Feng Xu, Pingping Hu, Mingyuan Zhang, Kehui Tong, Gang Ma, Yuemei Xu, Liang Zhu, and Jiande D. Z. Chen. 2018. “Needleless Transcutaneous Electrical Acustimulation: A Pilot Study Evaluating Improvement in Post-operative Recovery”. American Journal of Gastroenterology. Ovid Technologies (Wolters Kluwer Health). doi:10.1038/s41395-018-0156-y.
- Ma, Da, Ji-Sheng Han, Quan-Heng Diao, Gui-Fa Deng, Xing-Jie Ping, Wei-Jie Jin, Liu-Zhen Wu, Cai-Lian Cui, and Xiao-Dong Li. 2015. “Transcutaneous Electrical Acupoint Stimulation for the Treatment of Withdrawal Syndrome in Heroin Addicts”. Pain Medicine. Oxford University Press (OUP). doi:10.1111/pme.12738.
- Ma D, Han JS, Diao QH, Deng GF, Ping XJ, Jin WJ, Wu LZ, Cui CL, Li XD. Transcutaneous electrical acupoint stimulation for the treatment of withdrawal syndrome in heroin addicts. Pain Med. 2015 May;16(5):839-48. doi: 10.1111/pme.12738. Erratum In: Pain Med. 2015 Nov;16(11):2217.
- Qu F, Wang FF, Wu Y, Zhou J, Robinson N, Hardiman PJ, Pan JX, He YJ, Zhu YH, Wang HZ, Ye XQ, He KL, Cui L, Zhao HL, Ye YH. Transcutaneous Electrical Acupoint Stimulation Improves the Outcomes of In Vitro Fertilization: A Prospective, Randomized and Controlled Study. Explore (NY). 2017 Sep-Oct;13(5):306-312. doi: 10.1016/j.explore.2017.06.004. Epub 2017 Jun 30.
- Jiande Chen 2021. "Optimization of Transcutaneous Electrical Acustimulation (TEA) Modalities for Treatment of IBS-C". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT04953728.
Frequently Asked Questions
Does this medical trial require additional participants at present?
"According to clinicaltrials.gov, this research is presently recruiting participants. The trial was first published on the 1st of July 2021 and has since been updated most recently on the 30th of November 2022." - Anonymous Online Contributor
What criteria must an individual meet to qualify for participation in this research?
"Currently, the trial is attempting to source 25 individuals suffering from dyschezia aged between 18 and 99. To be eligible, they must agree to abide by all rules set out in the study, meet diagnostic criteria for IBS-C according to Rome IV standards, demonstrate a minimum of 3 months of associated symptoms before enrollment, report inadequate relief from their abdominal pain at both screening and randomization stages, as well as possess a VAS pain score higher than 3/10." - Anonymous Online Contributor
How many participants are being recruited to partake in this clinical trial?
"Affirmative. The clinical trial portal provides evidence that this medical research, which was originally published on 1st July 2021, is currently recruiting. 25 patients are being sought from a single site." - Anonymous Online Contributor
Does this trial accept individuals older than 45 years of age?
"This clinical trial is available to applicants aged 18-99. Patients under the age of 18 have 24 trials they can participate in, while those over 65 have 72 options." - Anonymous Online Contributor