← Back to Search

Cognitive Behavioral Therapy for Obsessive-Compulsive Disorder

N/A

Waitlist Available

Research Sponsored by University of Michigan

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Be younger than 18 years old

Timeline

Screening 3 weeks

Treatment Varies

Follow Up up to 16 weeks after baseline (following 12 weeks of therapy for intervention groups); approximately 15-20 minutes

Awards & highlights

Study Summary

This trial will study the effects of Obsessive-Compulsive Disorder (OCD) and cognitive behavioral therapy (CBT) on children by using magnetic resonance imaging (MRI) to assess the function and structure of task control circuits.

Eligible Conditions

Obsessive-Compulsive Disorder (OCD)

Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ up to 16 weeks after baseline (following 12 weeks of therapy for intervention groups);approximately 10 minutes

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~up to 16 weeks after baseline (following 12 weeks of therapy for intervention groups);approximately 10 minutes

This trial's timeline: 3 weeks for screening, Varies for treatment, and up to 16 weeks after baseline (following 12 weeks of therapy for intervention groups);approximately 10 minutes for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.

Primary outcome measures

Blood oxygen-level dependent (BOLD) functional MRI signal during a cognitive conflict task

Secondary outcome measures

Blood oxygen-level dependent (BOLD) functional connectivity MRI of task control circuits

Child Yale-Brown Obsessive Compulsive Scale

Obsessive Compulsive Inventory - Child Version (OCI-CV)

Side effects data

From 2021 Phase 4 trial • 12 Patients • NCT04135937

irritability

100%

80%

60%

40%

20%

Study treatment Arm

MESH

Trial Design

3Treatment groups

Experimental Treatment

Active Control

Group I: Subclinical Obsessive-Compulsive symptoms (OCS)Experimental Treatment1 Intervention

Group II: Obsessive Compulsive DisorderExperimental Treatment1 Intervention

Group III: Healthy ControlActive Control1 Intervention

Treatment

First Studied

Drug Approval Stage

How many patients have taken this drug

Cognitive Behavioral Therapy

2016

Completed Phase 4

~3120

Do I qualify?Apply below to find out

Find a Location

Who is running the clinical trial?

University of MichiganLead Sponsor

1,794 Previous Clinical Trials

6,373,747 Total Patients Enrolled

1 Trials studying Obsessive-Compulsive Disorder

206 Patients Enrolled for Obsessive-Compulsive Disorder

Columbia UniversityOTHER

1,431 Previous Clinical Trials

2,460,662 Total Patients Enrolled

5 Trials studying Obsessive-Compulsive Disorder

407 Patients Enrolled for Obsessive-Compulsive Disorder

National Institute of Mental Health (NIMH)NIH

2,782 Previous Clinical Trials

2,688,938 Total Patients Enrolled

65 Trials studying Obsessive-Compulsive Disorder

13,812 Patients Enrolled for Obsessive-Compulsive Disorder

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Are there still vacancies available for individuals to participate in this research?

"Correct. Records hosted on clinicaltrials.gov affirm that this research is still looking to bring in participants, with the initial posting being March 24th 2019 and a recent update coming September 1st 2022. The medical trial requires 105 patients at one site for enrolment."

Answered by AI

Could I potentially participate in this experiment?

"This clinical trial seeks to admit 105 minors aged 7-14 that possess compulsive personality. To be eligible, these patients must satisfy the following conditions: Official DSM-5 diagnosis of OCD as their primary concern; no psychotropic medication or current psychotherapy for OCD; written informed consent from both patient and parent/guardian, ability to comprehend English; absence of a lifetime DSM-5 diagnosis including major depressive disorder, substance/alcohol abuse, psychotic disorder, bipolar disorder, eating disorder or pervasive developmental disorders; willing abstention from medications on day of study scan (with exception to stable doses of stimulants or other ADHD drugs under investigator review);"

Answered by AI

What is the total number of participants in this clinical research project?

"Indeed, the registry hosted on clinicaltrials.gov shows that this research project is actively signing up participants. It was first posted in March 2019 and has been revised as recently as September 2022; 105 patients are required from 1 medical facility to complete it."

Answered by AI

Is the age restriction for this clinical trial limited to those under twenty years old?

"The requirements to participate in this medical trial stipulate that applicants must be between the ages of 7 and 14. In addition, there are 26 clinical trials for minors and 68 studies recruiting seniors."

Answered by AI

Recent research and studies

Depression and AnxietyJournal

Subcortical Shape in Pediatric and Adult Obsessive‐compulsive Disorder

Wang, Zhishun, Martine Fontaine, Marilyn Cyr, Moira A. Rynn, Helen Blair Simpson, Rachel Marsh, and David Pagliaccio. 2022. “Subcortical Shape in Pediatric and Adult Obsessive‐compulsive Disorder”. Depression and Anxiety. Wiley. doi:10.1002/da.23261.

clinicaltrials.govStudy

Task Control Circuit Targets for Obsessive Compulsive Behaviors in Children

Kate D. Fitzgerald 2019. "Task Control Circuit Targets for Obsessive Compulsive Behaviors in Children". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT03584945.