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KCI AbThera for Abdominal Compartment Syndrome (SAD Trial)

N/A

Waitlist Available

Led By Andrew W Kirkpatrick, MD

Research Sponsored by University of Calgary

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Be older than 18 years old

Timeline

Screening 3 weeks

Treatment Varies

Follow Up patients will be followed-up for 6 months

Awards & highlights

SAD Trial Summary

This trial is evaluating the effectiveness of actively removing peritoneal fluid through a commercial suction device compared to passive drainage of the same fluid drained through standard surgical drains.

Eligible Conditions

Abdominal Compartment Syndrome

SAD Trial Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ patients will be followed-up for 6 months

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~patients will be followed-up for 6 months

This trial's timeline: 3 weeks for screening, Varies for treatment, and patients will be followed-up for 6 months for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.

Primary outcome measures

Systemic inflammatory marker levels and peritoneal fluid inflammatory marker levels

Secondary outcome measures

Global Outcomes

Physiological Outcomes

SAD Trial Design

2Treatment groups

Experimental Treatment

Active Control

Group I: KCI AbTheraExperimental Treatment1 Intervention

commercial AbThera vacuum assisted abdominal closure at 125 mmHg suction

Group II: "Stampede" VACActive Control1 Intervention

Calgary-home-made "Stampede" VAC system with only closed drain bulb suction

Treatment

First Studied

Drug Approval Stage

How many patients have taken this drug

KCI AbThera

2011

N/A

~50

Do I qualify?Apply below to find out

Find a Location

Who is running the clinical trial?

University of CalgaryLead Sponsor

792 Previous Clinical Trials

869,104 Total Patients Enrolled

3MIndustry Sponsor

157 Previous Clinical Trials

31,424 Total Patients Enrolled

Alberta Health servicesOTHER

158 Previous Clinical Trials

649,616 Total Patients Enrolled

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Are there any spaces available for participants in this medical experiment?

"Confirmed, this trial is no longer actively seeking participants. The study was initially posted in June of 2011 and most recently amended on January 24th 2022. Nevertheless, there are 926 other clinical trials that have open recruitment at the present moment."

Answered by AI

Recent research and studies

Emergency Medicine JournalJournal

Abdominal Compartment Syndrome: An Emergency Department Perspective

Harrisson, S E, J E Smith, A W Lambert, and M J Midwinter. 2008. “Abdominal Compartment Syndrome: An Emergency Department Perspective”. Emergency Medicine Journal. BMJ. doi:10.1136/emj.2007.050344.

The Journal of Trauma: Injury, Infection, and Critical CareJournal

Intra-abdominal Complications After Surgical Repair of Small Bowel Injuries: An International Review

Kirkpatrick, Andrew W., Keith A. Baxter, Richard K. Simons, Eva Germann, Charles E. Lucas, and Anna M. Ledgerwood. 2003. “Intra-abdominal Complications After Surgical Repair of Small Bowel Injuries: An International Review”. The Journal of Trauma: Injury, Infection, and Critical Care. Ovid Technologies (Wolters Kluwer Health). doi:10.1097/01.ta.0000060248.87046.ee.

Langenbeck's Archives of SurgeryJournal

Current Insights in Intra-abdominal Hypertension and Abdominal Compartment Syndrome: Open the Abdomen and Keep It Open!

De laet, Inneke E., Mariska Ravyts, Wesley Vidts, Jody Valk, Jan J. De Waele, and Manu L. N. G. Malbrain. 2008. “Current Insights in Intra-abdominal Hypertension and Abdominal Compartment Syndrome: Open the Abdomen and Keep It Open!”. Langenbeck's Archives of Surgery. Springer Science and Business Media LLC. doi:10.1007/s00423-008-0347-x.

Intensive Care MedicineJournal