Online Mindfulness for Chemotherapy Side Effects
What You Need to Know Before You Apply
What is the purpose of this trial?
Background: Chemotherapy treatment (CT) can have burdensome side effects such as fatigue, nausea-vomiting, and sleep problems that can significantly affect patients' quality of life. Fatigue is the most common, lasting and bothersome of these, which prevents people from working and carrying out daily activities. Mindfulness-Based Cancer Recovery (MBCR) is an evidence-based group training program which has shown to help treat negative physical and psychosocial symptoms in cancer patients. The investigators propose to evaluate a pilot-tested online-MBCR program for patients undergoing CT who may be low on energy, time or have compromised immunity.Objectives: To evaluate the impact of participation in online MBCR during CT on fatigue (primary outcome), sleep, pain, nausea/vomiting, mood disturbance, stress symptoms and quality of life (secondary outcomes) as well as cognitive function and return to work (exploratory outcomes) over the course of treatment.Methods: The study design is a randomized wait-list controlled trial, conducted during CT for patients with breast or colorectal cancer. Participants will take the 12-week online MBCR program at home within 2 weeks of randomization (immediate group) or after CT completion (waitlist group). Outcomes will be assessed online at, 1) Baseline, 2) Post-MBCR, 3) Post-CT (primary outcome) and 4) 12 months post-baseline.Anticipated Findings: MBCR is a promising adjuvant program that could help patients prevent, delay or diminish aversive symptoms and side-effects associated with CT, particularly fatigue. If helpful, online-MBCR could be made easily available at cancer centers worldwide and significantly lessen the burden of cancer treatments.
Who Is on the Research Team?
Linda E Carlson, PhD
Principal Investigator
University of Calgary
Barry D Bultz, PhD
Principal Investigator
University of Calgary
Are You a Good Fit for This Trial?
This trial is for adults over 18 with stage I-III breast cancer or stage II-III colorectal cancer, about to start specific chemotherapy regimens. Participants need internet access and must be able to use a computer or smart device to attend online mindfulness sessions in English.Inclusion Criteria
Exclusion Criteria
Timeline for a Trial Participant
Screening
Participants are screened for eligibility to participate in the trial
Treatment
Participants undergo chemotherapy treatment while participating in a 12-week online Mindfulness-Based Cancer Recovery (MBCR) program
Follow-up
Participants are monitored for fatigue and other outcomes post-treatment
Waitlist Control
Participants in the waitlist control group receive the MBCR program after completing chemotherapy
What Are the Treatments Tested in This Trial?
Interventions
- Online Mindfulness Based Cancer Recovery (MBCR)
Find a Clinic Near You
Who Is Running the Clinical Trial?
University of Calgary
Lead Sponsor