750 Participants Needed

CORRECT Study of Minimal Residual Disease Detection in Colorectal Cancer

(MRD Trial)

Recruiting at 28 trial locations
ND
Overseen ByNSABP Department of Site and Study Management Department of Site and Study Management
Age: 18+
Sex: Any
Trial Phase: Academic
Sponsor: Exact Sciences Corporation
No Placebo GroupAll trial participants will receive the active study treatment (no placebo)

Trial Summary

What is the purpose of this trial?

The CORRECT - MRD II study will prospectively enroll patients who have undergone complete surgical resection for stage II or III colorectal cancer. Patients will be followed for a minimum of 3 years and up to 5 years for recurrence.

Eligibility Criteria

Inclusion Criteria

Diagnosis of carcinoma of the colon or rectum (patients with lymphomatous, sarcomatous, or neuroendocrine features are not eligible).
in the opinion of the surgeon, all grossly visible tumor was completely resected ("curative resection")
histologic evaluation by the pathologist confirms the margins of the resected specimens are not involved by malignant cells.
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Treatment Details

Interventions

  • MRD
Participant Groups
1Treatment groups
Experimental Treatment
Group I: Stage ll or lllExperimental Treatment1 Intervention
Patients with stage ll or lll colorectal cancer

Find a Clinic Near You

Who Is Running the Clinical Trial?

Exact Sciences Corporation

Lead Sponsor

Trials
36
Recruited
282,000+

NSABP Foundation Inc

Collaborator

Trials
89
Recruited
140,000+