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High Intensity Interval Exercise (HIIE) for Colorectal Cancer (CANEX-2 Trial)

N/A
Waitlist Available
Research Sponsored by Université de Sherbrooke
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up before the start of the condition (t = 0 minute), at the end of the condition (t = 50 minutes), 1 hour post-condition (t = 110 minutes), 2 hour post-condition (t = 170 minutes)
Awards & highlights

CANEX-2 Trial Summary

This study is evaluating the effect of a high-intensity interval training (HIIT) on the immune and inflammatory profile of patients undergoing chemotherapy.

Eligible Conditions
  • Colorectal Cancer

CANEX-2 Trial Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~before the start of the condition (t = 0 minute), at the end of the condition (t = 50 minutes), 1 hour post-condition (t = 110 minutes), 2 hour post-condition (t = 170 minutes)
This trial's timeline: 3 weeks for screening, Varies for treatment, and before the start of the condition (t = 0 minute), at the end of the condition (t = 50 minutes), 1 hour post-condition (t = 110 minutes), 2 hour post-condition (t = 170 minutes) for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Change in the concentration of different peripheral blood mononuclear cells (Natural Killer Cells, T cells and monocytes)
Secondary outcome measures
Cancer-Related Fatigue
Cerebral integrity - Cerebral blood flow
Change in the concentration of inflammatory mediators in peripheral blood (chemokines, pro- and anti-inflammatory cytokines)
+3 more

CANEX-2 Trial Design

3Treatment groups
Experimental Treatment
Active Control
Group I: Cancer patients without MRIExperimental Treatment3 Interventions
9 cancer patients will be recruited and received the 3 experimental conditions : first the rest condition, then randomly MICE condition and HIIT condition, all without MRI.
Group II: Cancer patients with MRIExperimental Treatment3 Interventions
9 cancer patients will be recruited and received the 3 experimental conditions : first the rest condition (with MRI), then randomly MICE condition and HIIT condition (with MRI).
Group III: Healthy patientsActive Control2 Interventions
9 healthy patients will be recruited and received 2 experimental conditions : first the rest condition (with a MRI), then HIIT condition (with MRI).

Find a Location

Who is running the clinical trial?

Université de SherbrookeLead Sponsor
292 Previous Clinical Trials
69,422 Total Patients Enrolled

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.
Recent research and studies
clinicaltrials.govStudy
Impact of Aerobic Exercise on Immune Response and Side Effects of Cancer Treatments
2020. "Impact of Aerobic Exercise on Immune Response and Side Effects of Cancer Treatments". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT04715061.
~4 spots leftby Apr 2025
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